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Spata32 spermatogenesis associated 32 [ Mus musculus (house mouse) ]

Gene ID: 328019, updated on 11-Apr-2024

Summary

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Official Symbol
Spata32provided by MGI
Official Full Name
spermatogenesis associated 32provided by MGI
Primary source
MGI:MGI:3045340
See related
Ensembl:ENSMUSG00000044787 AllianceGenome:MGI:3045340
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
VAD1.2; 4933400C05Rik
Summary
Predicted to enable actin binding activity. Predicted to be involved in spermatogenesis. Predicted to be active in perinuclear region of cytoplasm. Is expressed in brain; embryo; heart; spermatid; and testis. Orthologous to human SPATA32 (spermatogenesis associated 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 52.4) See more
Orthologs
human all
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Genomic context

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See Spata32 in Genome Data Viewer
Location:
11 E1; 11 66.77 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (103098953..103109258, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (103208127..103218432, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10717 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:103036322-103036635 Neighboring gene predicted gene, 51919 Neighboring gene uncharacterized LOC118567870 Neighboring gene formin-like 1 Neighboring gene EF-hand calcium binding domain 15 Neighboring gene predicted gene, 51920 Neighboring gene mitogen-activated protein kinase kinase kinase 14 Neighboring gene predicted gene, 34823 Neighboring gene STARR-positive B cell enhancer ABC_E10718 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:103128947-103129269 Neighboring gene STARR-seq mESC enhancer starr_30841 Neighboring gene STARR-seq mESC enhancer starr_30842 Neighboring gene STARR-positive B cell enhancer ABC_E3026 Neighboring gene Rho GTPase activating protein 27 Neighboring gene Rho GTPase activating protein 27, opposite strand 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of an acrosome protein VAD1.2/AEP2 which is differentially expressed in spermatogenesis. Lee KF, et al. Mol Hum Reprod, 2008 Aug. PMID 18621766
  2. Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display. Luk JM, et al. Biochem Biophys Res Commun, 2003 Aug 8. PMID 12878178
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification and expression analysis of the rat VAD1.2 ortholog.
    Title: Identification of novel genes expressed during spermatogenesis in stage-synchronized rat testes by differential display.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in spermatogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
spermatogenesis-associated protein 32
Names
acrosome expressed protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177801.3 → NP_808469.1  spermatogenesis-associated protein 32

    See identical proteins and their annotated locations for NP_808469.1

    Status: PROVISIONAL

    Source sequence(s)
    AK077068
    Consensus CDS
    CCDS25515.1
    UniProtKB/Swiss-Prot
    Q8C5V0
    Related
    ENSMUSP00000099365.2, ENSMUST00000103076.2
    Conserved Domains (1) summary
    pfam15310
    Location:106 → 329
    VAD1-2; Vitamin A-deficiency (VAD) rat model signalling

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    103098953..103109258 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156780.1 → XP_036012673.1  spermatogenesis-associated protein 32 isoform X2

    Conserved Domains (1) summary
    pfam15310
    Location:36 → 259
    VAD1-2; Vitamin A-deficiency (VAD) rat model signalling

  2. XM_036156779.1 → XP_036012672.1  spermatogenesis-associated protein 32 isoform X2

    Conserved Domains (1) summary
    pfam15310
    Location:36 → 259
    VAD1-2; Vitamin A-deficiency (VAD) rat model signalling

  3. XM_006533582.5 → XP_006533645.1  spermatogenesis-associated protein 32 isoform X1

    Conserved Domains (1) summary
    pfam15310
    Location:118 → 341
    VAD1-2; Vitamin A-deficiency (VAD) rat model signalling
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C5V0.1 GenPept UniProtKB/Swiss-Prot:Q8C5V0

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