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ALDH6A1 aldehyde dehydrogenase 6 family member A1 [ Bos taurus (cattle) ]

Gene ID: 327692, updated on 5-Mar-2024

Summary

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Official Symbol
ALDH6A1provided by VGNC
Official Full Name
aldehyde dehydrogenase 6 family member A1provided by VGNC
Primary source
VGNC:VGNC:25817
See related
BGD:BT19864; Ensembl:ENSBTAG00000018469
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See ALDH6A1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (85427564..85447592, complement)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene FAM161 centrosomal protein B Neighboring gene coenzyme Q6, monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 (inactive) Neighboring gene basal body orientation factor 1 Neighboring gene lin-52 DREAM MuvB core complex component Neighboring gene visual system homeobox 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel use of an iodo-myristyl-CoA analog identifies a semialdehyde dehydrogenase in bovine liver. Deichaite I, et al. J Biol Chem, 1993 Jun 25. PMID 8514806
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables malonate-semialdehyde dehydrogenase (acetylating) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in thymine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in valine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
Names
MMSDH
aldehyde dehydrogenase family 6 member A1
malonate-semialdehyde dehydrogenase
NP_787005.1
XP_024853065.1
XP_024853066.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175811.2 → NP_787005.1  methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor

    See identical proteins and their annotated locations for NP_787005.1

    Status: PROVISIONAL

    Source sequence(s)
    L08643
    UniProtKB/Swiss-Prot
    Q07536
    UniProtKB/TrEMBL
    F1N7K8
    Related
    ENSBTAP00000081890.1, ENSBTAT00000128278.1
    Conserved Domains (1) summary
    cd07085
    Location:42 → 518
    ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    85427564..85447592 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024997298.2 → XP_024853066.1  methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform X1

    UniProtKB/TrEMBL
    F1N7K8
    Conserved Domains (1) summary
    cd07085
    Location:1 → 438
    ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2

  2. XM_024997297.2 → XP_024853065.1  methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform X1

    UniProtKB/TrEMBL
    F1N7K8
    Conserved Domains (1) summary
    cd07085
    Location:1 → 438
    ALDH_F6_MMSDH; Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07536.1 GenPept UniProtKB/Swiss-Prot:Q07536

Gene LinkOut

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