gopc golgi-associated PDZ and coiled-coil motif containing [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gopcprovided by ZNC
Official Full Name: golgi-associated PDZ and coiled-coil motif containingprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5086
See related: Ensembl:ENSDARG00000023117 AllianceGenome:ZFIN:ZDB-GENE-030131-5086
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fe38f01; zgc:56254; zgc:65853; wu:fe38f01
Summary: Predicted to enable transmembrane transporter binding activity. Predicted to be involved in cytoplasmic sequestering of CFTR protein and negative regulation of protein localization to cell surface. Predicted to be active in Golgi apparatus; membrane; and trans-Golgi network transport vesicle. Orthologous to human GOPC (golgi associated PDZ and coiled-coil motif containing). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (42246899..42281434)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (42349788..42384324)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables transmembrane transporter binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of protein localization to cell surface	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in trans-Golgi network transport vesicle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Golgi-associated PDZ and coiled-coil motif-containing protein

Names: PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200557.1 → NP_956851.1 Golgi-associated PDZ and coiled-coil motif-containing protein

See identical proteins and their annotated locations for NP_956851.1

Status: PROVISIONAL

Source sequence(s)

BC056565

UniProtKB/TrEMBL

A0A8M1PFC7, Q6PHG0

Related

ENSDARP00000061134.5, ENSDART00000061135.7

Conserved Domains (1) summary

cd00992
Location:285 → 367

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007131.7 Reference GRCz11 Primary Assembly

Range

42246899..42281434

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005170172.4 → XP_005170229.1 Golgi-associated PDZ and coiled-coil motif-containing protein isoform X1

UniProtKB/TrEMBL

A0A8M2BHK3

Conserved Domains (1) summary

cd00992
Location:277 → 359

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...