ddx39aa DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ddx39aaprovided by ZNC
Official Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4275
See related: Ensembl:ENSDARG00000006225 AllianceGenome:ZFIN:ZDB-GENE-030131-4275
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ddx39a; zgc:55881; wu:fc87b12
Summary: Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in mRNA export from nucleus and mRNA splicing, via spliceosome. Orthologous to human DDX39A (DExD-box helicase 39A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (45205920..45215284, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (44504617..44513981, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IBA Inferred from Biological aspect of Ancestor more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa

Names: DEAD (Asp-Glu-Ala-Asp) box polypeptide 39a; Eukaryotic initiation factor 4a

NP_001315271.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001328342.1 → NP_001315271.1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa

Status: VALIDATED

Source sequence(s)

EH433199, EH444410, EH559791, EH570750

UniProtKB/TrEMBL

A0A8M1P8Z3, A2AWA1

Related

ENSDARP00000008513.6, ENSDART00000014727.8

Conserved Domains (3) summary

PTZ00424
Location:19 → 417

PTZ00424; helicase 45; Provisional

cd00079
Location:263 → 389

HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...

cd00268
Location:46 → 249

DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

45205920..45215284 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_199721.1: Suppressed sequence

Description

NM_199721.1: This RefSeq was removed because currently there is insufficient support for the transcript.