U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

septin6 septin 6 [ Danio rerio (zebrafish) ]

Gene ID: 322694, updated on 11-Apr-2024

Summary

Official Symbol
septin6provided by ZNC
Official Full Name
septin 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1414
See related
Ensembl:ENSDARG00000010721 AllianceGenome:ZFIN:ZDB-GENE-030131-1414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Sep2; sept6; fc54b04; zgc:66071; wu:fb70g05; wu:fc54b04; wu:fl76c07
Summary
Predicted to enable GTPase activity and molecular adaptor activity. Acts upstream of or within cilium assembly and determination of left/right symmetry. Located in cilium. Is expressed in several structures, including Kupffer's vesicle; axis; hypochord; nervous system; and pronephros. Orthologous to human SEPTIN6 (septin 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (33297781..33328026, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (32957467..32987712, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene START domain containing 14 Neighboring gene RAB41, member RAS oncogene family Neighboring gene sosondowah ankyrin repeat domain family d Neighboring gene ribosomal protein L39

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cell division site IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of septin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in septin ring IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212626.2NP_997791.2  septin-6

    Status: VALIDATED

    Source sequence(s)
    BX571981
    UniProtKB/TrEMBL
    A0A8M2BL09, F1R3Q3
    Related
    ENSDARP00000121708.1, ENSDART00000137997.3
    Conserved Domains (2) summary
    cd01850
    Location:45312
    CDC_Septin; CDC/Septin GTPase family
    COG5019
    Location:25378
    CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    33297781..33328026 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005173240.4XP_005173297.1  septin-6 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BKJ7
    Conserved Domains (2) summary
    cd01850
    Location:45312
    CDC_Septin; CDC/Septin GTPase family
    COG5019
    Location:25378
    CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
  2. XM_005173239.3XP_005173296.1  septin-6 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BKJ6
    Conserved Domains (2) summary
    cd01850
    Location:45312
    CDC_Septin; CDC/Septin GTPase family
    COG5019
    Location:25378
    CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
  3. XM_005173242.4XP_005173299.1  septin-6 isoform X3

    UniProtKB/TrEMBL
    A0A8M2BL09, F1R3Q3
    Conserved Domains (2) summary
    cd01850
    Location:45312
    CDC_Septin; CDC/Septin GTPase family
    COG5019
    Location:25378
    CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]

RNA

  1. XR_225093.4 RNA Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394917.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    262798..291832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)