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Zfp629 zinc finger protein 629 [ Mus musculus (house mouse) ]

Gene ID: 320683, updated on 11-Apr-2024

Summary

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Official Symbol
Zfp629provided by MGI
Official Full Name
zinc finger protein 629provided by MGI
Primary source
MGI:MGI:2444524
See related
Ensembl:ENSMUSG00000045639 AllianceGenome:MGI:2444524
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf629; 9330199A09Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system; limb mesenchyme; nervous system; and retina layer. Orthologous to human ZNF629 (zinc finger protein 629). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 8.7), whole brain E14.5 (RPKM 7.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp629 in Genome Data Viewer
Location:
7 F3; 7 69.62 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127206203..127215053, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127607028..127615785, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 40 Neighboring gene RIKEN cDNA 1700120K04 gene Neighboring gene predicted gene, 51458 Neighboring gene predicted gene, 53373

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  2. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 629

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362196.2 → NP_001349125.1  zinc finger protein 629 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC122417
    Consensus CDS
    CCDS21873.1
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0
    Related
    ENSMUSP00000081612.4, ENSMUST00000084564.10
    Conserved Domains (3) summary
    COG5048
    Location:203 → 511
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:179 → 199
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:149 → 171
    zf-C2H2; Zinc finger, C2H2 type

  2. NM_001362197.2 → NP_001349126.1  zinc finger protein 629 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC122417
    Consensus CDS
    CCDS21873.1
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0
    Related
    ENSMUSP00000113903.2, ENSMUST00000122066.8
    Conserved Domains (3) summary
    COG5048
    Location:203 → 511
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:179 → 199
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:149 → 171
    zf-C2H2; Zinc finger, C2H2 type

  3. NM_001404400.1 → NP_001391329.1  zinc finger protein 629 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC122417
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0

  4. NM_001404402.1 → NP_001391331.1  zinc finger protein 629 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC122417
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0

  5. NM_001404403.1 → NP_001391332.1  zinc finger protein 629 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC122417
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0

  6. NM_001404404.1 → NP_001391333.1  zinc finger protein 629 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC122417
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0

  7. NM_001404405.1 → NP_001391334.1  zinc finger protein 629 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC122417

  8. NM_177226.7 → NP_796200.1  zinc finger protein 629 isoform a

    See identical proteins and their annotated locations for NP_796200.1

    Status: VALIDATED

    Source sequence(s)
    AC122417
    Consensus CDS
    CCDS21873.1
    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0
    Related
    ENSMUSP00000053760.6, ENSMUST00000058038.12
    Conserved Domains (3) summary
    COG5048
    Location:203 → 511
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:179 → 199
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:149 → 171
    zf-C2H2; Zinc finger, C2H2 type

RNA

  1. NR_155450.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122417

  2. NR_155451.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122417

  3. NR_155452.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122417

  4. NR_175840.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122417

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    127206203..127215053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241833.4 → XP_011240135.1  zinc finger protein 629 isoform X2

    See identical proteins and their annotated locations for XP_011240135.1

    UniProtKB/Swiss-Prot
    Q6A085, Q8BG88, Q8BIR0
    Conserved Domains (3) summary
    COG5048
    Location:203 → 511
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:179 → 199
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:149 → 171
    zf-C2H2; Zinc finger, C2H2 type

  2. XM_006507952.4 → XP_006508015.1  zinc finger protein 629 isoform X1

    Conserved Domains (3) summary
    PHA03169
    Location:118 → 269
    PHA03169; hypothetical protein; Provisional
    COG5048
    Location:251 → 629
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:288 → 308
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6A085.2 GenPept UniProtKB/Swiss-Prot:Q6A085

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