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Zfp182 zinc finger protein 182 [ Mus musculus (house mouse) ]

Gene ID: 319535, updated on 21-Apr-2024

Summary

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Official Symbol
Zfp182provided by MGI
Official Full Name
zinc finger protein 182provided by MGI
Primary source
MGI:MGI:2442220
See related
Ensembl:ENSMUSG00000054737 AllianceGenome:MGI:2442220
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf182; 6330583I20Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF182 (zinc finger protein 182). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 2.4), CNS E18 (RPKM 2.3) and 20 other tissues See more
Orthologs
human all
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Genomic context

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Location:
X A1.3; X 16.55 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (20892423..20928357, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (21026184..21062113, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46888 Neighboring gene ELK1, member of ETS oncogene family Neighboring gene RIKEN cDNA A230072C01 gene Neighboring gene ubiquitously expressed prefoldin like chaperone Neighboring gene STARR-seq mESC enhancer starr_46890 Neighboring gene STARR-seq mESC enhancer starr_46891 Neighboring gene sperm acrosome associated 5 Neighboring gene zinc finger protein 300

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 182
Names
zinc finger protein 21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013387.2 → NP_001013405.2  zinc finger protein 182

    See identical proteins and their annotated locations for NP_001013405.2

    Status: VALIDATED

    Source sequence(s)
    AK032094, AK045698, AK048587, BB231943, BB574195, BC063066
    Consensus CDS
    CCDS40887.1
    UniProtKB/TrEMBL
    A2AE18
    Related
    ENSMUSP00000110989.3, ENSMUST00000115333.9
    Conserved Domains (3) summary
    smart00349
    Location:8 → 84
    KRAB; krueppel associated box
    COG5048
    Location:233 → 622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001111076.1 → NP_001104546.1  zinc finger protein 182

    See identical proteins and their annotated locations for NP_001104546.1

    Status: VALIDATED

    Source sequence(s)
    AK032094, AK043973, AK045698, AK048587, BB231943, BB574195, BC063066
    Consensus CDS
    CCDS40887.1
    UniProtKB/TrEMBL
    A2AE18
    Related
    ENSMUSP00000045005.6, ENSMUST00000040628.6
    Conserved Domains (3) summary
    smart00349
    Location:8 → 84
    KRAB; krueppel associated box
    COG5048
    Location:233 → 622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    20892423..20928357 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251367.2 → XP_030107227.1  zinc finger protein 182 isoform X3

    UniProtKB/TrEMBL
    A2AE18
    Conserved Domains (3) summary
    smart00349
    Location:8 → 84
    KRAB; krueppel associated box
    COG5048
    Location:233 → 622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_030251369.2 → XP_030107229.1  zinc finger protein 182 isoform X5

    Conserved Domains (2) summary
    COG5048
    Location:113 → 502
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:145 → 165
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_030251365.2 → XP_030107225.1  zinc finger protein 182 isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:43 → 119
    KRAB; krueppel associated box
    COG5048
    Location:268 → 657
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:300 → 320
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_036161979.1 → XP_036017872.1  zinc finger protein 182 isoform X3

    UniProtKB/TrEMBL
    A2AE18
    Conserved Domains (3) summary
    smart00349
    Location:8 → 84
    KRAB; krueppel associated box
    COG5048
    Location:233 → 622
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:265 → 285
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_036161981.1 → XP_036017874.1  zinc finger protein 182 isoform X5

    Conserved Domains (2) summary
    COG5048
    Location:113 → 502
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:145 → 165
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. XM_036161978.1 → XP_036017871.1  zinc finger protein 182 isoform X1

    Related
    ENSMUSP00000110990.2, ENSMUST00000115334.8
    Conserved Domains (3) summary
    smart00349
    Location:63 → 139
    KRAB; krueppel associated box
    COG5048
    Location:288 → 677
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:320 → 340
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. XM_036161980.1 → XP_036017873.1  zinc finger protein 182 isoform X4

    Conserved Domains (3) summary
    smart00349
    Location:5 → 81
    KRAB; krueppel associated box
    COG5048
    Location:230 → 619
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:262 → 282
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P560.1 GenPept UniProtKB/Swiss-Prot:Q6P560

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