Ankef1 ankyrin repeat and EF-hand domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ankef1provided by MGI
Official Full Name: ankyrin repeat and EF-hand domain containing 1provided by MGI
Primary source: MGI:MGI:2441685
See related: Ensembl:ENSMUSG00000074771 AllianceGenome:MGI:2441685
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ankrd5
Summary: Is expressed in eye and genitourinary system. Orthologous to human ANKEF1 (ankyrin repeat and EF-hand domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward testis adult (RPKM 46.7) See more
Orthologs: human all
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Genomic context

Location:: 2 F3; 2 67.46 cM

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (136374241..136397774)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (136532321..136555854)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: ankyrin repeat and EF-hand domain-containing protein 1

Names: ankyrin repeat domain 5; ankyrin repeat domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175667.4 → NP_783598.1 ankyrin repeat and EF-hand domain-containing protein 1

See identical proteins and their annotated locations for NP_783598.1

Status: PROVISIONAL

Source sequence(s)

BC120825

Consensus CDS

CCDS38249.1

UniProtKB/Swiss-Prot

Q0VB20, Q9D2J7

Related

ENSMUSP00000113881.2, ENSMUST00000121717.2

Conserved Domains (4) summary

cd00204
Location:519 → 643

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:529 → 621

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:527 → 555

ANK; ANK repeat [structural motif]

cl08302
Location:340 → 395

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...