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CG10962 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31824, updated on 4-Apr-2024

Summary

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Official Symbol
CG10962provided by FlyBase
Primary source
FLYBASE:FBgn0030073
Locus tag
Dmel_CG10962
See related
AllianceGenome:FB:FBgn0030073
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7090; Dmel\CG10962
Summary
Predicted to enable 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; 17-beta-ketosteroid reductase activity; and 3-keto sterol reductase activity. Is expressed in several structures, including embryonic/larval visceral muscle cell; presumptive embryonic/larval digestive system; and wing disc. Orthologous to human DHRS11 (dehydrogenase/reductase 11). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
8C1-8C1; 1-26 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8972908..8974255, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8866941..8868288, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene retinal degeneration A Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43836 Neighboring gene mir-4964 stem loop Neighboring gene uncharacterized protein Neighboring gene mir-31b stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression profiling of Drosophila imaginal discs. Klebes A, et al. Genome Biol, 2002 Jul 24. PMID 12186645, Free PMC Article
  2. Joint estimates of quantitative trait locus effect and frequency using synthetic recombinant populations of Drosophila melanogaster. Macdonald SJ, et al. Genetics, 2007 Jun. PMID 17435224, Free PMC Article
  3. Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin. Cox RT, et al. Dis Model Mech, 2009 Sep-Oct. PMID 19638420, Free PMC Article
  4. Female Genetic Contributions to Sperm Competition in Drosophila melanogaster. Chen DS, et al. Genetics, 2019 Jul. PMID 31101677, Free PMC Article
  5. Divergent transcriptomic responses to repeated and single cold exposures in Drosophila melanogaster. Zhang J, et al. J Exp Biol, 2011 Dec 1. PMID 22071194

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 17-beta-hydroxysteroid dehydrogenase (NADP+) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables 17-beta-ketosteroid reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables 3-keto sterol reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables estradiol 17-beta-dehydrogenase [NAD(P)] activity ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10962-PB
NP_788887.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    8972908..8974255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176714.3 → NP_788887.1  uncharacterized protein Dmel_CG10962 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788887.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IRN0, Q95R56
    Related
    FBpp0071206
    Conserved Domains (2) summary
    COG4221
    Location:1 → 249
    YdfG; NADP-dependent 3-hydroxy acid dehydrogenase YdfG [Energy production and conversion]
    cl21454
    Location:1 → 243
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IRN0 Q8IRN0
Q95R56 Q95R56

Gene LinkOut

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