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elavl3 ELAV like neuron-specific RNA binding protein 3 [ Danio rerio (zebrafish) ]

Gene ID: 30732, updated on 5-May-2024

Summary

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Official Symbol
elavl3provided by ZNC
Official Full Name
ELAV like neuron-specific RNA binding protein 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-980526-76
See related
Ensembl:ENSDARG00000014420 AllianceGenome:ZFIN:ZDB-GENE-980526-76
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
HuC; elrc; zHuC; id:ibd1248; wu:fb77b03
Summary
Predicted to enable RNA binding activity. Acts upstream of or within regulation of neurogenesis. Predicted to be part of ribonucleoprotein complex. Is expressed in several structures, including nervous system; neural plate; neural tube; neuronal stem cell; and presumptive structure. Orthologous to human ELAVL3 (ELAV like RNA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (46798511..46817871, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (48847856..48865537, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkey-248g21.1 Neighboring gene phosphodiesterase 4A, cAMP-specific Neighboring gene PRKCSH beta subunit of glucosidase II Neighboring gene uncharacterized LOC103910324 Neighboring gene potassium sodium-activated channel subfamily T member 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. PyZebrascope: An Open-Source Platform for Brain-Wide Neural Activity Imaging in Zebrafish. Barbara R, et al. Front Cell Dev Biol, 2022. PMID 35663407, Free PMC Article
  2. Differential impact of dose-range glyphosate on locomotor behavior, neuronal activity, glio-cerebrovascular structures, and transcript regulations in zebrafish larvae. Forner-Piquer I, et al. Chemosphere, 2021 Mar. PMID 33359984
  3. Bright and High-Performance Genetically Encoded Ca(2+) Indicator Based on mNeonGreen Fluorescent Protein. Zarowny L, et al. ACS Sens, 2020 Jul 24. PMID 32571014
  4. FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity. Barykina NV, et al. Int J Mol Sci, 2020 Apr 24. PMID 32344594, Free PMC Article
  5. Hybrid light-sheet and light-field microscope for high resolution and large volume neuroimaging. Wang D, et al. Biomed Opt Express, 2019 Dec 1. PMID 31853419, Free PMC Article

See all (313) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ELAV-like protein 3
Names
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
elav-related C
elavC
embryonic lethal, abnormal vision-related C
etID309927.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131449.1 → NP_571524.1  ELAV-like protein 3

    See identical proteins and their annotated locations for NP_571524.1

    Status: PROVISIONAL

    Source sequence(s)
    U62018
    UniProtKB/TrEMBL
    P79736
    Related
    ENSDARP00000012109.7, ENSDART00000013717.9
    Conserved Domains (3) summary
    cd12650
    Location:37 → 114
    RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
    TIGR01661
    Location:35 → 344
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    cl17169
    Location:261 → 345
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    46798511..46817871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017353190.2 → XP_017208679.1  ELAV-like protein 3 isoform X6

    UniProtKB/TrEMBL
    A0A8M6Z446

  2. XM_005164220.4 → XP_005164277.1  ELAV-like protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A0R4IC33, A0A8M2BBP9
    Related
    ENSDARP00000130425.2, ENSDART00000166505.3
    Conserved Domains (1) summary
    TIGR01661
    Location:35 → 357
    ELAV_HUD_SF; ELAV/HuD family splicing factor

  3. XM_005164218.4 → XP_005164275.1  ELAV-like protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BBS5
    Conserved Domains (4) summary
    cd12650
    Location:37 → 114
    RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
    cd12655
    Location:281 → 365
    RRM3_HuC; RNA recognition motif 3 in vertebrate Hu-antigen C (HuC)
    TIGR01661
    Location:35 → 364
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    cl17169
    Location:119 → 208
    RRM_SF; RNA recognition motif (RRM) superfamily

  4. XM_017353191.2 → XP_017208680.1  ELAV-like protein 3 isoform X7

    UniProtKB/TrEMBL
    A0A8M6YUY6
    Conserved Domains (1) summary
    cl25887
    Location:35 → 345
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  5. XM_017353188.2 → XP_017208677.1  ELAV-like protein 3 isoform X5

    UniProtKB/TrEMBL
    A0A8M6YXB4

  6. XM_005164219.4 → XP_005164276.1  ELAV-like protein 3 isoform X3

    See identical proteins and their annotated locations for XP_005164276.1

    UniProtKB/TrEMBL
    A0A8M2BBG3, Q6P105
    Related
    ENSDARP00000030680.6, ENSDART00000028610.8
    Conserved Domains (1) summary
    TIGR01661
    Location:35 → 358
    ELAV_HUD_SF; ELAV/HuD family splicing factor

  7. XM_009299733.3 → XP_009298008.1  ELAV-like protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AYA7
    Conserved Domains (4) summary
    cd12650
    Location:37 → 114
    RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
    cd12655
    Location:282 → 366
    RRM3_HuC; RNA recognition motif 3 in vertebrate Hu-antigen C (HuC)
    TIGR01661
    Location:35 → 365
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    cl17169
    Location:119 → 209
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein
Heading Accession and Version

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