cdh2 - cadherin 2, type 1, N-cadherin (neuronal)
Predicted to enable cadherin binding activity and calcium ion binding activity. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and nervous system development. Located in perinuclear region of cytoplasm and presynaptic membrane. Part of catenin complex. Is expressed in several structures, including germ ring; immature eye; mesoderm; nervous system; and pericardial region. Human ortholog(s) of this gene implicated in agenesis of corpus callosum, cardiac, ocular, and genital syndrome; arrhythmogenic right ventricular cardiomyopathy; and arrhythmogenic right ventricular dysplasia 14. Orthologous to human CDH2 (cadherin 2). [provided by Alliance of Genome Resources, Apr 2022]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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