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Acyp1 acylphosphatase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299203, updated on 30-Mar-2024

Summary

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Official Symbol
Acyp1provided by RGD
Official Full Name
acylphosphatase 1provided by RGD
Primary source
RGD:1311327
See related
Ensembl:ENSRNOG00000006744 AllianceGenome:RGD:1311327
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable acylphosphatase activity. Orthologous to human ACYP1 (acylphosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 215.0), Thymus (RPKM 163.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
6q31
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (110650213..110663404, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (104919162..104932348, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (109097065..109110266, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene mutL homolog 3 Neighboring gene zinc finger, C2HC-type containing 1C Neighboring gene NIMA-related kinase 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables acylphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
acylphosphatase-1
Names
acylphosphatase 1, erythrocyte (common) type
NP_001100216.1
NP_001186096.1
NP_001186097.1
XP_006240370.1
XP_017449587.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106746.2 → NP_001100216.1  acylphosphatase-1

    See identical proteins and their annotated locations for NP_001100216.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    FM062949, JAXUCZ010000006
    UniProtKB/TrEMBL
    A6JE20, D4A6X4
    Related
    ENSRNOP00000009086.5, ENSRNOT00000009086.7
    Conserved Domains (1) summary
    pfam00708
    Location:10 → 97
    Acylphosphatase

  2. NM_001199167.1 → NP_001186096.1  acylphosphatase-1

    See identical proteins and their annotated locations for NP_001186096.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6JE20, D4A6X4
    Conserved Domains (1) summary
    pfam00708
    Location:10 → 97
    Acylphosphatase

  3. NM_001199168.1 → NP_001186097.1  acylphosphatase-1

    See identical proteins and their annotated locations for NP_001186097.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    FM034312, JAXUCZ010000006
    UniProtKB/TrEMBL
    A6JE20, D4A6X4
    Conserved Domains (1) summary
    pfam00708
    Location:10 → 97
    Acylphosphatase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    110650213..110663404 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594098.3 → XP_017449587.1  acylphosphatase-1 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K899
    Related
    ENSRNOP00000074525.2

  2. XM_006240308.5 → XP_006240370.1  acylphosphatase-1 isoform X2

    See identical proteins and their annotated locations for XP_006240370.1

    UniProtKB/TrEMBL
    A6JE20, D4A6X4
    Conserved Domains (1) summary
    pfam00708
    Location:10 → 97
    Acylphosphatase
Nucleotide Protein Strain
Heading Accession and Version

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