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Tmem255b transmembrane protein 255B [ Mus musculus (house mouse) ]

Gene ID: 272465, updated on 30-Apr-2024

Summary

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Official Symbol
Tmem255bprovided by MGI
Official Full Name
transmembrane protein 255Bprovided by MGI
Primary source
MGI:MGI:2685533
See related
Ensembl:ENSMUSG00000038457 AllianceGenome:MGI:2685533
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm687; Fam70b
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in utricle and vagus ganglion. Orthologous to human TMEM255B (transmembrane protein 255B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 1.7), mammary gland adult (RPKM 1.2) and 19 other tissues See more
Orthologs
human all
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Genomic context

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Location:
8 A1.1; 8 6.0 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (13485118..13543434)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (13435113..13493434)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ATPase, H+/K+ exchanging, beta polypeptide Neighboring gene G protein-coupled receptor kinase 1 Neighboring gene growth arrest specific 6 Neighboring gene predicted gene, 53399 Neighboring gene RIKEN cDNA 1700029H14 gene Neighboring gene STARR-seq mESC enhancer starr_20769 Neighboring gene RAS p21 protein activator 3 Neighboring gene predicted gene, 34795

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Clone Names

  • FLJ20716

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 255B
Names
family with sequence similarity 70, member B
protein FAM70B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143671.1 → NP_001137143.1  transmembrane protein 255B isoform 1

    See identical proteins and their annotated locations for NP_001137143.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK131817, BC089620
    Consensus CDS
    CCDS52486.1
    UniProtKB/TrEMBL
    G3UWB7
    Related
    ENSMUSP00000130504.2, ENSMUST00000167505.3
    Conserved Domains (2) summary
    pfam13273
    Location:31 → 104
    DUF4064; Protein of unknown function (DUF4064)
    pfam14967
    Location:16 → 327
    FAM70; FAM70 protein

  2. NM_001143672.1 → NP_001137144.1  transmembrane protein 255B isoform 2

    See identical proteins and their annotated locations for NP_001137144.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK131817, BC089620
    Consensus CDS
    CCDS52487.1
    UniProtKB/TrEMBL
    G5E908
    Related
    ENSMUSP00000127421.2, ENSMUST00000167071.9
    Conserved Domains (1) summary
    pfam14967
    Location:16 → 306
    FAM70; FAM70 protein

  3. NM_001402814.1 → NP_001389743.1  transmembrane protein 255B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC130818

  4. NM_001402815.1 → NP_001389744.1  transmembrane protein 255B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC130818, AC134613

  5. NM_001402816.1 → NP_001389745.1  transmembrane protein 255B isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AC130818

  6. NM_001402817.1 → NP_001389746.1  transmembrane protein 255B isoform 6 precursor

    Status: VALIDATED

    Source sequence(s)
    AC130818, AC134613

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    13485118..13543434
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508813.5 → XP_006508876.1  transmembrane protein 255B isoform X3

    Conserved Domains (1) summary
    pfam14967
    Location:1 → 188
    FAM70; FAM70 protein

  2. XM_006508811.5 → XP_006508874.1  transmembrane protein 255B isoform X2

    Conserved Domains (1) summary
    pfam14967
    Location:16 → 253
    FAM70; FAM70 protein

  3. XM_006508814.5 → XP_006508877.1  transmembrane protein 255B isoform X4

    Conserved Domains (1) summary
    pfam14967
    Location:16 → 275
    FAM70; FAM70 protein

RNA

  1. XR_004934836.1 RNA Sequence

  2. XR_003947295.2 RNA Sequence

  3. XR_004934837.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5FW56.3 GenPept UniProtKB/Swiss-Prot:Q5FW56

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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