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Zbtb47 zinc finger and BTB domain containing 47 [ Mus musculus (house mouse) ]

Gene ID: 270210, updated on 5-Mar-2024

Summary

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Official Symbol
Zbtb47provided by MGI
Official Full Name
zinc finger and BTB domain containing 47provided by MGI
Primary source
MGI:MGI:2670992
See related
Ensembl:ENSMUSG00000013419 AllianceGenome:MGI:2670992
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp651; 4732420M22Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZBTB47 (zinc finger and BTB domain containing 47). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 20.0), heart adult (RPKM 16.7) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Zbtb47 in Genome Data Viewer
Location:
9 F4; 9 72.6 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (121588210..121600808)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (121759319..121771742)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1400 Neighboring gene SS18, nBAF chromatin remodeling complex subunit like 2 Neighboring gene STARR-positive B cell enhancer ABC_E10593 Neighboring gene natural killer tumor recognition sequence Neighboring gene RIKEN cDNA E530011L22 gene Neighboring gene STARR-positive B cell enhancer ABC_E6812 Neighboring gene kelch-like 40 Neighboring gene hedgehog acyltransferase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger and BTB domain-containing protein 47
Names
zinc finger protein 651

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166644.1 → NP_001160116.1  zinc finger and BTB domain-containing protein 47

    Status: VALIDATED

    Source sequence(s)
    AC165080
    Consensus CDS
    CCDS52968.1
    UniProtKB/TrEMBL
    E9PZ11
    Related
    ENSMUSP00000091286.4, ENSMUST00000093772.4
    Conserved Domains (6) summary
    smart00225
    Location:46 → 141
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:641 → 690
    COG5048; FOG: Zn-finger [General function prediction only]
    TIGR04104
    Location:588 → 632
    cxxc_20_cxxc; cxxc_20_cxxc protein
    sd00017
    Location:589 → 609
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:32 → 138
    BTB; BTB/POZ domain
    pfam13465
    Location:657 → 680
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    121588210..121600808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512145.5 → XP_006512208.1  zinc finger and BTB domain-containing protein 47 isoform X1

    Conserved Domains (5) summary
    PLN03086
    Location:405 → 479
    PLN03086; PRLI-interacting factor K; Provisional
    COG5048
    Location:613 → 662
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:555 → 638
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:561 → 581
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18231
    Location:1 → 114
    BTB_POZ_ZBTB47_ZNF651; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 47 (ZBTB47)

  2. XM_006512146.2 → XP_006512209.1  zinc finger and BTB domain-containing protein 47 isoform X2

    UniProtKB/TrEMBL
    A0A1L1STM6
    Conserved Domains (3) summary
    PLN03086
    Location:433 → 507
    PLN03086; PRLI-interacting factor K; Provisional
    sd00017
    Location:476 → 495
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18231
    Location:29 → 142
    BTB_POZ_ZBTB47_ZNF651; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 47 (ZBTB47)

RNA

  1. XR_001778915.2 RNA Sequence

  2. XR_004935442.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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