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Abhd18 abhydrolase domain containing 18 [ Mus musculus (house mouse) ]

Gene ID: 269423, updated on 5-Mar-2024

Summary

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Official Symbol
Abhd18provided by MGI
Official Full Name
abhydrolase domain containing 18provided by MGI
Primary source
MGI:MGI:1915468
See related
Ensembl:ENSMUSG00000037818 AllianceGenome:MGI:1915468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310068E01Rik; 3110057O12Rik
Summary
Predicted to be located in extracellular region. Is expressed in dorsal root ganglion. Orthologous to human ABHD18 (abhydrolase domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 6.0), frontal lobe adult (RPKM 3.4) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
3 B; 3 19.58 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (40825532..40892573)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (40871095..40938138)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 8 Neighboring gene STARR-positive B cell enhancer ABC_E1617 Neighboring gene predicted gene 2011 Neighboring gene FUN14 domain containing 2 pseudogene Neighboring gene RIKEN cDNA 6430590A07 gene Neighboring gene FUN14 domain containing 2B Neighboring gene STARR-positive B cell enhancer ABC_E7910 Neighboring gene STARR-seq mESC enhancer starr_07475 Neighboring gene La ribonucleoprotein 1B Neighboring gene predicted gene, 22043 Neighboring gene predicted gene 42437

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • 4732404H23

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein ABHD18
Names
abhydrolase domain-containing protein 18
alpha/beta hydrolase domain-containing protein 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001377110.1 → NP_001364039.1  protein ABHD18 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC160757
    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    pfam09752
    Location:1 → 381
    DUF2048; Abhydrolase domain containing 18

  2. NM_001377111.1 → NP_001364040.1  protein ABHD18 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variant 4, encodes isoform c.
    Source sequence(s)
    AC160757
    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    cl21494
    Location:1 → 330
    Abhydrolase; alpha/beta hydrolases

  3. NM_001377112.1 → NP_001364041.1  protein ABHD18 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variant 3, encodes isoform c.
    Source sequence(s)
    AC160757
    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    cl21494
    Location:1 → 330
    Abhydrolase; alpha/beta hydrolases

  4. NM_026622.4 → NP_080898.2  protein ABHD18 isoform a precursor

    See identical proteins and their annotated locations for NP_080898.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AC160757
    Consensus CDS
    CCDS38422.2
    UniProtKB/Swiss-Prot
    Q3TQS7, Q562E0, Q8C0I3, Q8C1A9
    Related
    ENSMUSP00000124430.2, ENSMUST00000159774.7
    Conserved Domains (1) summary
    pfam09752
    Location:16 → 457
    DUF2048; Abhydrolase domain containing 18

RNA

  1. NR_165084.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC160757, BC051081
    Related
    ENSMUST00000204496.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    40825532..40892573
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319591.2 → XP_017175080.1  protein ABHD18 isoform X1

    UniProtKB/Swiss-Prot
    Q3TQS7, Q562E0, Q8C0I3, Q8C1A9
    Conserved Domains (1) summary
    pfam09752
    Location:16 → 457
    DUF2048; Abhydrolase domain containing 18

  2. XM_030252629.2 → XP_030108489.1  protein ABHD18 isoform X3

    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    cl21494
    Location:1 → 288
    Abhydrolase; alpha/beta hydrolases

  3. XM_017319592.3 → XP_017175081.1  protein ABHD18 isoform X3

    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    cl21494
    Location:1 → 288
    Abhydrolase; alpha/beta hydrolases

  4. XM_036163124.1 → XP_036019017.1  protein ABHD18 isoform X3

    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    cl21494
    Location:1 → 288
    Abhydrolase; alpha/beta hydrolases

  5. XM_006500779.3 → XP_006500842.1  protein ABHD18 isoform X2

    See identical proteins and their annotated locations for XP_006500842.1

    UniProtKB/TrEMBL
    B7ZNF5
    Conserved Domains (1) summary
    pfam09752
    Location:1 → 381
    DUF2048; Abhydrolase domain containing 18

RNA

  1. XR_001783694.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C1A9.1 GenPept UniProtKB/Swiss-Prot:Q8C1A9

Gene LinkOut

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