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Ly6g5b lymphocyte antigen 6 family member G5B [ Mus musculus (house mouse) ]

Gene ID: 266614, updated on 5-Mar-2024

Summary

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Official Symbol
Ly6g5bprovided by MGI
Official Full Name
lymphocyte antigen 6 family member G5Bprovided by MGI
Primary source
MGI:MGI:2385809
See related
Ensembl:ENSMUSG00000043807 AllianceGenome:MGI:2385809
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Colocalizes with external side of plasma membrane. Is expressed in several structures, including brain; liver; lung; metanephros; and spleen. Orthologous to human LY6G5B (lymphocyte antigen 6 family member G5B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 782.9) See more
Orthologs
human all
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Genomic context

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Location:
17 B1; 17 18.59 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35332920..35337534, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35113944..35118558, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7527 Neighboring gene abhydrolase domain containing 16A Neighboring gene lymphocyte antigen 6 family member G5C Neighboring gene casein kinase 2, beta polypeptide Neighboring gene G patch domain and ankyrin repeats 1 Neighboring gene predicted gene 20522 Neighboring gene DNA segment, Chr 17, human D6S53E

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Intron retention and transcript chimerism conserved across mammals: Ly6g5b and Csnk2b-Ly6g5b as examples. Hernández-Torres F, et al. BMC Genomics, 2013 Mar 22. PMID 23521802, Free PMC Article
  2. Transcriptional analysis of a novel cluster of LY-6 family members in the human and mouse major histocompatibility complex: five genes with many splice forms. Mallya M, et al. Genomics, 2002 Jul. PMID 12079290
  3. Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands. Mallya M, et al. Protein Sci, 2006 Oct. PMID 17008713, Free PMC Article
  4. Organization, evolution and functions of the human and mouse Ly6/uPAR family genes. Loughner CL, et al. Hum Genomics, 2016 Apr 21. PMID 27098205, Free PMC Article
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Potential readthrough

Included gene: Csnk2b

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NOT enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
colocalizes_with external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
colocalizes_with external side of plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
colocalizes_with external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
lymphocyte antigen 6 complex locus protein G5b
Names
lymphocyte antigen 6 complex, locus G5B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001371035.1 → NP_001357964.1  lymphocyte antigen 6 complex locus protein G5b isoform 2

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Consensus CDS
    CCDS89083.1
    Related
    ENSMUSP00000138033.2, ENSMUST00000172854.2

  2. NM_148939.3 → NP_683741.1  lymphocyte antigen 6 complex locus protein G5b isoform 1 precursor

    See identical proteins and their annotated locations for NP_683741.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    CR974444
    Consensus CDS
    CCDS28683.1
    UniProtKB/Swiss-Prot
    Q3U982, Q8K1T4
    UniProtKB/TrEMBL
    N0E6I7
    Related
    ENSMUSP00000052133.5, ENSMUST00000062657.5

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    35332920..35337534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K1T4.1 GenPept UniProtKB/Swiss-Prot:Q8K1T4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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