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atg5 autophagy-associated protein Atg5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540814, updated on 11-Apr-2024

Summary

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Gene symbol
atg5
Gene description
autophagy-associated protein Atg5
Primary source
PomBase:SPBC4B4.10c
Locus tag
SPBC4B4.10c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
mug77
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Genomic context

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Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (3432104..3433533, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ESCRT II complex subunit Vps25 Neighboring gene U1 snRNP-associated protein Usp102 Neighboring gene hexose transporter Ght2 Neighboring gene U1 snRNP-associated protein Usp105 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pantothenate transporter Liz1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of inorganic polyphosphate is required for proper vacuolar proteolysis in fission yeast. Sawada N, et al. J Biol Chem, 2021 Jul. PMID 34147496, Free PMC Article
  2. Atg20- and Atg24-family proteins promote organelle autophagy in fission yeast. Zhao D, et al. J Cell Sci, 2016 Nov 15. PMID 27737912
  3. Atg38-Atg8 interaction in fission yeast establishes a positive feedback loop to promote autophagy. Yu ZQ, et al. Autophagy, 2020 Nov. PMID 31941401, Free PMC Article
  4. Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation. Mukaiyama H, et al. Microbiology (Reading), 2009 Dec. PMID 19778961
  5. Global analysis of fission yeast mating genes reveals new autophagy factors. Sun LL, et al. PLoS Genet, 2013. PMID 23950735, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to Atg8-family ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables Atg8-family ligase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to nitrogen starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in macroautophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nucleophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein lipidation involved in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in reticulophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Atg12-Atg5-Atg16 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Atg12-Atg5-Atg16 complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in autophagosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in mitochondria-associated endoplasmic reticulum membrane contact site IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in phagophore IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in phagophore assembly site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in phagophore assembly site membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in phagophore assembly site membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
autophagy-associated protein Atg5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3432104..3433533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022346.2 → NP_596427.1  autophagy-associated protein Atg5 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596427.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74971
    Conserved Domains (1) summary
    pfam04106
    Location:73 → 259
    APG5; Autophagy protein Apg5
Nucleotide Protein
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