Zfp11 zinc finger protein 11 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp11provided by MGI
Official Full Name: zinc finger protein 11provided by MGI
Primary source: MGI:MGI:99156
See related: Ensembl:ENSMUSG00000051034 AllianceGenome:MGI:99156
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Krox-6; Zfp-11; 6720465D24
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including eye; genitourinary system; liver; tail; and trunk somite. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in whole brain E14.5 (RPKM 2.1), CNS E18 (RPKM 2.0) and 28 other tissues See more
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Genomic context

Location:: 5 G1.3; 5 68.22 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (129731659..129747152, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (129654595..129670088, complement)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:235325

Zfp11 (e-PCR), detects polymorphism
- UniSTS:496747

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 11

Names: protein Krox-6.1A/6.1B+/6.1B-; zinc finger protein Krox-6.1A/6.1B+/6.1B-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_172462.4 → NP_766050.1 zinc finger protein 11

See identical proteins and their annotated locations for NP_766050.1

Status: VALIDATED

Source sequence(s)

AK032872, AK085077, BB623389

Consensus CDS

CCDS39291.1

UniProtKB/Swiss-Prot

B2RTF0, P10751, P10752, P10753, Q505E4, Q6PDR5, Q8BSI2, Q8C3R5

Related

ENSMUSP00000051861.7, ENSMUST00000049778.7

Conserved Domains (4) summary

COG5048
Location:83 → 460

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:423 → 443

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:520 → 544

zf-H2C2_2; Zinc-finger double domain

cl19237
Location:308 → 349

DUF45; Protein of unknown function DUF45