U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Plekhs1 pleckstrin homology domain containing, family S member 1 [ Mus musculus (house mouse) ]

Gene ID: 226245, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Plekhs1provided by MGI
Official Full Name
pleckstrin homology domain containing, family S member 1provided by MGI
Primary source
MGI:MGI:2443041
See related
Ensembl:ENSMUSG00000035818 AllianceGenome:MGI:2443041
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9930023K05Rik
Summary
Orthologous to human PLEKHS1 (pleckstrin homology domain containing S1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in subcutaneous fat pad adult (RPKM 8.4), ovary adult (RPKM 3.3) and 1 other tissue See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Plekhs1 in Genome Data Viewer
Location:
19 D2; 19 51.86 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (56445705..56475161)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (56457275..56486729)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46523 Neighboring gene caspase 7 Neighboring gene predicted gene, 46657 Neighboring gene predicted gene, 53193 Neighboring gene DNA cross-link repair 1A Neighboring gene NHL repeat containing 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
    Title: PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC99964

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
pleckstrin homology domain-containing family S member 1
Names
PH domain-containing family S member 1
PH domain-containing protein C10orf81 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164263.1 → NP_001157735.1  pleckstrin homology domain-containing family S member 1 isoform 2

    See identical proteins and their annotated locations for NP_001157735.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses two alternate in-frame splice sites in the 5' coding region, compared to variant 1. Although the variants have slightly different sequences, their lengths are the same. Variant 2 encodes isoform 2, which has a slightly different sequence but is the same length as isoform 1.
    Source sequence(s)
    AC166746, AK036908
    Consensus CDS
    CCDS57148.1
    UniProtKB/Swiss-Prot
    Q8BW88
    Related
    ENSMUSP00000136674.2, ENSMUST00000178590.9
    Conserved Domains (2) summary
    pfam00169
    Location:21 → 127
    PH; PH domain
    cl17171
    Location:26 → 126
    PH-like; Pleckstrin homology-like domain

  2. NM_172641.3 → NP_766229.2  pleckstrin homology domain-containing family S member 1 isoform 1

    See identical proteins and their annotated locations for NP_766229.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AC166746, AK036908, AK053921
    Consensus CDS
    CCDS29916.1
    UniProtKB/Swiss-Prot
    E9QMW0, Q5EAT4, Q8BW88, Q8BZ18, Q8R5A9
    Related
    ENSMUSP00000035440.7, ENSMUST00000039666.8
    Conserved Domains (1) summary
    cl17171
    Location:26 → 127
    PH-like; Pleckstrin homology-like domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    56445705..56475161
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527018.3 → XP_006527081.1  pleckstrin homology domain-containing family S member 1 isoform X1

    See identical proteins and their annotated locations for XP_006527081.1

    UniProtKB/Swiss-Prot
    E9QMW0, Q5EAT4, Q8BW88, Q8BZ18, Q8R5A9
    Conserved Domains (1) summary
    cl17171
    Location:26 → 127
    PH-like; Pleckstrin homology-like domain

  2. XM_006527022.5 → XP_006527085.1  pleckstrin homology domain-containing family S member 1 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BW88.2 GenPept UniProtKB/Swiss-Prot:Q8BW88

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous