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vit-4 Vitellogenin-4 [ Caenorhabditis elegans ]

Gene ID: 180646, updated on 23-Nov-2023

Summary

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Gene symbol
vit-4
Gene description
Vitellogenin-4
Primary source
WormBase:WBGene00006928
Locus tag
CELE_F59D8.2
See related
AllianceGenome:WB:WBGene00006928
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: X
Exon count:
6
Sequence:
Chromosome: X; NC_003284.9 (3558769..3563965, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Glycogenin-1 Neighboring gene C2 domain-containing protein;RGS domain-containing protein;Regulator of G-protein signaling rgs-7 Neighboring gene ncRNA Neighboring gene Vitellogenin-3 Neighboring gene ncRNA Neighboring gene GST N-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alternatively spliced transcripts of the flp-1 gene encode distinct FMRFamide-like peptides in Caenorhabditis elegans. Rosoff ML, et al. J Neurosci, 1992 Jun. PMID 1607945, Free PMC Article
  2. Transcriptome Profile Reveals that Pu-Erh Tea Represses the Expression of Vitellogenin Family to Reduce Fat Accumulation in Caenorhabditis elegans. Xiao RY, et al. Molecules, 2016 Oct 17. PMID 27763516, Free PMC Article
  3. Endoplasmic Reticulum Stress Caused by Lipoprotein Accumulation Suppresses Immunity against Bacterial Pathogens and Contributes to Immunosenescence. Singh J, et al. mBio, 2017 May 30. PMID 28559483, Free PMC Article
  4. The C. elegans vitellogenin genes: short sequence repeats in the promoter regions and homology to the vertebrate genes. Spieth J, et al. Nucleic Acids Res, 1985 Jul 25. PMID 4022780, Free PMC Article
  5. The nucleotide sequence of a nematode vitellogenin gene. Spieth J, et al. Nucleic Acids Res, 1985 Oct 11. PMID 3855245, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables nutrient reservoir activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Vitellogenin-4
NP_508612.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    3558769..3563965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076211.8 → NP_508612.1  Vitellogenin-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508612.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P18947, Q9BPP3
    Conserved Domains (3) summary
    smart00216
    Location:1300 → 1454
    VWD; von Willebrand factor (vWF) type D domain
    pfam01347
    Location:24 → 617
    Vitellogenin_N; Lipoprotein amino terminal region
    pfam09172
    Location:651 → 942
    DUF1943; Domain of unknown function (DUF1943)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P18947.3

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