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zip-8 bZIP transcription factor 8 [ Caenorhabditis elegans ]

Gene ID: 175924, updated on 25-Apr-2024

Summary

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Gene symbol
zip-8
Gene description
bZIP transcription factor 8
Primary source
WormBase:WBGene00017755
Locus tag
CELE_F23F12.9
See related
AllianceGenome:WB:WBGene00017755
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in developing hermaphrodite gonad and intestine. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (6478955..6481243)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ANK_REP_REGION domain-containing protein;DUF223 domain-containing protein;DUF3668 domain-containing protein Neighboring gene ABC transporter domain-containing protein Neighboring gene ncRNA Neighboring gene CHiTin Binding domain (ChtBD2) containing

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GATA transcription factor required for immunity to bacterial and fungal pathogens. Kerry S, et al. PLoS One, 2006 Dec 20. PMID 17183709, Free PMC Article
  2. Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Reinke AW, et al. Science, 2013 May 10. PMID 23661758, Free PMC Article
  3. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
bZIP transcription factor 8
NP_498426.1
  • Confirmed by transcript evidence
NP_871665.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6478955..6481243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_181936.7 → NP_871665.1  bZIP transcription factor 8 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871665.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P46505

  2. NM_066025.5 → NP_498426.1  bZIP transcription factor 8 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498426.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P46505, Q8IG25
    Conserved Domains (1) summary
    cd14813
    Location:68 → 119
    bZIP_BmCbz-like; Basic leucine zipper (bZIP) domain of Bombyx mori chorion b-ZIP transcription factor and similar bZIP domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P46505.1

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