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swsn-7 ARID domain-containing protein;SWI/SNF nucleosome remodeling complex component [ Caenorhabditis elegans ]

Gene ID: 174286, updated on 3-Mar-2024

Summary

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Gene symbol
swsn-7
Gene description
ARID domain-containing protein;SWI/SNF nucleosome remodeling complex component
Primary source
WormBase:WBGene00007433
Locus tag
CELE_C08B11.3
See related
AllianceGenome:WB:WBGene00007433
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity. Is expressed in intestine and nervous system. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6; colorectal cancer; and hepatocellular carcinoma. Orthologous to human ARID2 (AT-rich interaction domain 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (8022632..8027763, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Early embryogenesis protein zyg-11 Neighboring gene ncRNA Neighboring gene Putative histone deacetylase 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nose resistant to fluoxetine protein 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comprehensive single cell-resolution analysis of the role of chromatin regulators in early C. elegans embryogenesis. Krüger AV, et al. Dev Biol, 2015 Feb 15. PMID 25446273
  2. SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans. Mathies LD, et al. Proc Natl Acad Sci U S A, 2015 Mar 10. PMID 25713357, Free PMC Article
  3. A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target. Andachi Y. RNA, 2008 Nov. PMID 18824511, Free PMC Article
  4. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
  5. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SWI/SNF superfamily-type complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ARID domain-containing protein;SWI/SNF nucleosome remodeling complex component
NP_001348697.1
  • Confirmed by transcript evidence
NP_495679.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8022632..8027763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001361864.4 → NP_001348697.1  ARID domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2K5ATP7
    Conserved Domains (2) summary
    smart00501
    Location:25 → 116
    BRIGHT; ARID (A/T-rich interaction domain) domain
    pfam15790
    Location:1088 → 1199
    EP400_N; E1A-binding protein p400, N-terminal

  2. NM_063278.6 → NP_495679.1  SWI/SNF nucleosome remodeling complex component [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495679.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09441
    Conserved Domains (1) summary
    smart00501
    Location:25 → 116
    BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09441.1

Gene LinkOut

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