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LOC128924190 CapStarr-seq enhancer MGSCv37_chr1:157001032-157001362 [ Mus musculus (house mouse) ]

Gene ID: 128924190, updated on 8-Feb-2024

Summary

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Gene symbol
LOC128924190
Gene description
CapStarr-seq enhancer MGSCv37_chr1:157001032-157001362
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region was identified as a candidate cis-regulatory module (CRM) in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. It was validated as an active enhancer by luciferase reporter assays in P5424 T cells. A subregion was also validated as an enhancer by high-throughput CapStarr-seq reporter assays showing strong activity in P5424 T cells. [provided by RefSeq, Mar 2023]
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Genomic context

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See LOC128924190 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155029559..155030065)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41981 Neighboring gene predicted gene, 30922 Neighboring gene major histocompatibility complex, class I-related Neighboring gene STARR-positive B cell enhancer ABC_E2569 Neighboring gene STARR-positive B cell enhancer ABC_E500 Neighboring gene syntaxin 6 Neighboring gene high mobility group protein B3 pseudogene Neighboring gene cDNA sequence BC034090 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157081058-157081259 Neighboring gene predicted gene, 31102

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq. Vanhille L, et al. Nat Commun, 2015 Apr 15. PMID 25872643

GeneRIFs: Gene References Into Functions

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_149972.1 

    Range
    101..607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    155029559..155030065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version