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LOC127889706 H3K4me1 hESC enhancer GRCh37_chr18:76819471-76819970 [ Homo sapiens (human) ]

Gene ID: 127889706, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127889706
Gene description
H3K4me1 hESC enhancer GRCh37_chr18:76819471-76819970
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127889706 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (79059471..79059970)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (79308611..79309110)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:76736667-76737380 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:76741235-76742064 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr18:76743410-76744168 Neighboring gene NANOG hESC enhancer GRCh37_chr18:76744863-76745377 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:76753804-76754785 Neighboring gene long intergenic non-protein coding RNA 1896 Neighboring gene uncharacterized LOC105372225 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr18:76766909-76768108 Neighboring gene spalt like transcription factor 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:76816919-76817092 Neighboring gene ATPase phospholipid transporting 9B (putative) Neighboring gene uncharacterized LOC124904331 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:76905122-76905630 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:76905631-76906137 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13536 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr18:76941895-76942463 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9568 Neighboring gene MPRA-validated peak3193 silencer Neighboring gene MED14-independent group 3 enhancer GRCh37_chr18:77005320-77006519 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9569 Neighboring gene VISTA enhancer hs775 Neighboring gene uncharacterized LOC105372226 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13537

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_139222.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    79059471..79059970
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003315961.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    130021..130520
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187666.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    128184..128683
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    79308611..79309110
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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