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LOC127458174 NANOG hESC enhancer GRCh37_chr7:153895575-153896144 [ Homo sapiens (human) ]

Gene ID: 127458174, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127458174
Gene description
NANOG hESC enhancer GRCh37_chr7:153895575-153896144
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (154198490..154199059)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (155373738..155374307)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986722 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:153555187-153556386 Neighboring gene dipeptidyl peptidase like 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:153583199-153583700 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:153632460-153632651 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:153640855-153641356 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:153641357-153641856 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:153686082-153686582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:153748374-153748976 Neighboring gene uncharacterized LOC101929998 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:153797461-153797962 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:153880891-153881704 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:153881705-153882518 Neighboring gene uncharacterized LOC105375582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:153991562-153992062 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:154376061-154376644 Neighboring gene uncharacterized LOC105375581

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_112947.1 

    Range
    101..670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    154198490..154199059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    155373738..155374307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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