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LOC127457529 H3K4me1 hESC enhancer GRCh37_chr7:122553899-122554408 [ Homo sapiens (human) ]

Gene ID: 127457529, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127457529
Gene description
H3K4me1 hESC enhancer GRCh37_chr7:122553899-122554408
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127457529 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (122913845..122914354)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (124230418..124230927)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene calcium dependent secretion activator 2 Neighboring gene uncharacterized LOC124901738 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:122458991-122459843 Neighboring gene RELA proto-oncogene, NF-kB subunit pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26565 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18578 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18579 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18580 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18581 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:122553388-122553898 Neighboring gene uncharacterized LOC105375482 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:122572022-122572522 Neighboring gene NANOG hESC enhancer GRCh37_chr7:122627466-122627971 Neighboring gene taste 2 receptor member 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_112303.1 

    Range
    101..610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    122913845..122914354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    124230418..124230927
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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