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LOC127273818 NANOG hESC enhancer GRCh37_chr2:80557197-80557699 [ Homo sapiens (human) ]

Gene ID: 127273818, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127273818
Gene description
NANOG hESC enhancer GRCh37_chr2:80557197-80557699
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (80330072..80330574)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (80330211..80330713)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene catenin alpha 2 Neighboring gene uncharacterized LOC107985903 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:80458363-80459016 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:80530694-80531319 Neighboring gene uncharacterized LOC107985904 Neighboring gene uncharacterized LOC105374824 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:80591811-80592596 Neighboring gene NANOG hESC enhancer GRCh37_chr2:80592898-80593415 Neighboring gene leucine rich repeat transmembrane neuronal 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:80689235-80689740 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:80688730-80689234 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:80709895-80710095 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11685 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16095 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16096 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16097 Neighboring gene NANOG hESC enhancer GRCh37_chr2:81005685-81006186 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:81101296-81102149 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:81103634-81104173 Neighboring gene uncharacterized LOC105374827 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:81147049-81147550

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_095668.1 

    Range
    101..603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    80330072..80330574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    80330211..80330713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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