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ADAM23 ADAM metallopeptidase domain 23 [ Varanus komodoensis (Komodo dragon) ]

Gene ID: 123024416, updated on 22-Mar-2024

Summary

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Gene symbol
ADAM23
Gene description
ADAM metallopeptidase domain 23
Locus tag
EYD10_10119
See related
Ensembl:ENSVKKG00000018541
Gene type
protein coding
RefSeq status
MODEL
Organism
Varanus komodoensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus
Also known as
ADAM23_0; ADAM23_1; ADAM23_2; ADAM23_3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
29
Annotation release Status Assembly Chr Location
100 current ASM479886v1 (GCF_004798865.1) Unplaced Scaffold NW_025335627.1 (17809384..18002685, complement)

NW_025335627.1Genomic Context describing neighboring genes Neighboring gene FAST kinase domains 2 Neighboring gene malate dehydrogenase 1B Neighboring gene zinc finger DBF-type containing 2 Neighboring gene chemerin chemokine-like receptor 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_025335627 Unplaced Scaffold Reference ASM479886v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in presynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 23
Names
Disintegrin and metalloproteinase domain-containing protein 23

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Varanus komodoensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM479886v1

Genomic

  1. NW_025335627.1 Reference ASM479886v1

    Range
    17809384..18002685 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044432108.1 → XP_044288043.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X6

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  2. XM_044432104.1 → XP_044288039.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X2

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  3. XM_044432111.1 → XP_044288046.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X8

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  4. XM_044432103.1 → XP_044288038.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X1

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  5. XM_044432105.1 → XP_044288040.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X3

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  6. XM_044432106.1 → XP_044288041.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X4

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  7. XM_044432110.1 → XP_044288045.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X7

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  8. XM_044432109.1 → XP_044288044.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X7

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  9. XM_044432107.1 → XP_044288042.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X5

    UniProtKB/TrEMBL
    A0A8D2LW97
    Related
    ENSVKKP00000028706.1, ENSVKKT00000029391.1
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 726
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

  10. XM_044432112.1 → XP_044288047.1  disintegrin and metalloproteinase domain-containing protein 23 isoform X9

    UniProtKB/TrEMBL
    A0A8D2LW97
    Conserved Domains (3) summary
    smart00050
    Location:510 → 583
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:585 → 692
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:296 → 493
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

RNA

  1. XR_006414921.1 RNA Sequence

    Related
    ENSVKKT00000029397.1
Nucleotide Protein
Heading Accession and Version

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