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apex2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 [ Polypterus senegalus (gray bichir) ]

Gene ID: 120542589, updated on 21-Mar-2024

Summary

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Gene symbol
apex2
Gene description
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Locus tag
GTO96_0007245
Gene type
protein coding
RefSeq status
MODEL
Organism
Polypterus senegalus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Polypteriformes; Polypteridae; Polypterus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 13
Exon count:
6
Annotation release Status Assembly Chr Location
100 current ASM1683550v1 (GCF_016835505.1) 13 NC_053166.1 (68357790..68370097)

Chromosome 13 - NC_053166.1Genomic Context describing neighboring genes Neighboring gene 5'-nucleotidase domain containing 2 Neighboring gene uncharacterized LOC120542034 Neighboring gene uncharacterized LOC120541867 Neighboring gene interleukin-17 receptor D-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053166.1 Chromosome 13 Reference ASM1683550v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA 3'-5' DNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-(apurinic or apyrimidinic site) lyase 2
Names
APEX2 lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Polypterus senegalus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1683550v1 Primary Assembly

Genomic

  1. NC_053166.1 Reference ASM1683550v1 Primary Assembly

    Range
    68357790..68370097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039775155.1 → XP_039631089.1  DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8X7WT98
    Conserved Domains (1) summary
    cd09088
    Location:2 → 318
    Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases

  2. XM_039775156.1 → XP_039631090.1  DNA-(apurinic or apyrimidinic site) lyase 2 isoform X2

    UniProtKB/TrEMBL
    A0A8X7WT98
    Conserved Domains (1) summary
    cd09088
    Location:2 → 269
    Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases
Nucleotide Protein
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