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APAF1 apoptotic peptidase activating factor 1 [ Crotalus tigris (Tiger rattlesnake) ]

Gene ID: 120312825, updated on 21-Mar-2024

Summary

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Gene symbol
APAF1
Gene description
apoptotic peptidase activating factor 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Crotalus tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
29
Annotation release Status Assembly Chr Location
100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024097071.1 (444798..505707)

NW_024097071.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA53 Neighboring gene solute carrier family 25 member 3 Neighboring gene IKBKB interacting protein Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene bridge-like lipid transfer protein family member 3B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024097071 Unplaced Scaffold Reference ASM1654583v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of apoptosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptotic protease-activating factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1654583v1

Genomic

  1. NW_024097071.1 Reference ASM1654583v1

    Range
    444798..505707
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039354047.1 → XP_039209981.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_039354044.1 → XP_039209978.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains

  3. XM_039354042.1 → XP_039209976.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains

  4. XM_039354041.1 → XP_039209975.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains

  5. XM_039354040.1 → XP_039209974.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains

  6. XM_039354043.1 → XP_039209977.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains

  7. XM_039354045.1 → XP_039209979.1  apoptotic protease-activating factor 1

    Conserved Domains (5) summary
    cd00200
    Location:614 → 906
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:144 → 374
    NB-ARC; NB-ARC domain
    pfam17908
    Location:453 → 587
    APAF1_C; APAF-1 helical domain
    cl14633
    Location:7 → 91
    DD; Death Domain Superfamily of protein-protein interaction domains
Nucleotide Protein
Heading Accession and Version

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