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ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Chelonoidis abingdonii (Abingdon island giant tortoise) ]

Gene ID: 116835135, updated on 18-Mar-2024

Summary

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Gene symbol
ABL1
Gene description
ABL proto-oncogene 1, non-receptor tyrosine kinase
See related
Ensembl:ENSCABG00000004751
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonoidis abingdonii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Testudinidae; Chelonoidis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current ASM359739v1 (GCF_003597395.1) Unplaced Scaffold NW_022644366.1 (7150195..7281508)

NW_022644366.1Genomic Context describing neighboring genes Neighboring gene PR/SET domain 12 Neighboring gene exosome component 2 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene fibrinogen C domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_022644366 Unplaced Scaffold Reference ASM359739v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ABL1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonoidis abingdonii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM359739v1

Genomic

  1. NW_022644366.1 Reference ASM359739v1

    Range
    7150195..7281508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032797666.1 → XP_032653557.1  tyrosine-protein kinase ABL1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0GCX9, A0A8C0GGP3
    Related
    ENSCABP00000006867.1, ENSCABT00000007501.1
    Conserved Domains (4) summary
    smart00808
    Location:1019 → 1143
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:142 → 235
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:84 → 137
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:254 → 516
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  2. XM_032797664.1 → XP_032653555.1  tyrosine-protein kinase ABL1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0GGP3
    Conserved Domains (4) summary
    smart00808
    Location:1024 → 1148
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:147 → 240
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:89 → 142
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:259 → 521
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  3. XM_032797670.1 → XP_032653561.1  tyrosine-protein kinase ABL1 isoform X7

    UniProtKB/TrEMBL
    A0A8C0GGP3
    Conserved Domains (3) summary
    smart00808
    Location:829 → 953
    FABD; F-actin binding domain (FABD)
    cd05052
    Location:64 → 326
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    cl15255
    Location:13 → 45
    SH2; Src homology 2 (SH2) domain

  4. XM_032797665.1 → XP_032653556.1  tyrosine-protein kinase ABL1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0GGP3
    Conserved Domains (4) summary
    smart00808
    Location:1022 → 1146
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:145 → 238
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:87 → 140
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:257 → 519
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  5. XM_032797667.1 → XP_032653558.1  tyrosine-protein kinase ABL1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0GGP3
    Conserved Domains (4) summary
    smart00808
    Location:1009 → 1133
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:132 → 225
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:74 → 127
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:244 → 506
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  6. XM_032797668.1 → XP_032653559.1  tyrosine-protein kinase ABL1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0IN39
    Conserved Domains (4) summary
    smart00808
    Location:1002 → 1126
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:125 → 218
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:67 → 120
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:237 → 499
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  7. XM_032797669.1 → XP_032653560.1  tyrosine-protein kinase ABL1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0GGP3
    Related
    ENSCABP00000006909.1, ENSCABT00000007549.1
    Conserved Domains (4) summary
    smart00808
    Location:984 → 1108
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:107 → 200
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:49 → 102
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:219 → 481
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
Nucleotide Protein
Heading Accession and Version

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