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Zfp607b zinc finger protein 607B [ Mus musculus (house mouse) ]

Gene ID: 112415, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp607bprovided by MGI
Official Full Name
zinc finger protein 607Bprovided by MGI
Primary source
MGI:MGI:2148237
See related
Ensembl:ENSMUSG00000057093 AllianceGenome:MGI:2148237
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C030039L03Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in bladder; male associated reproductive structure; testis; and urethra of male. Orthologous to human ZNF780A (zinc finger protein 780A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 3.0), testis adult (RPKM 2.2) and 10 other tissues See more
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Genomic context

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Location:
7 A3; 7 15.96 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (27374086..27405909)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27674661..27706484)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38973 Neighboring gene mitogen-activated protein kinase kinase kinase 10 Neighboring gene tetratricopeptide repeat domain 9B Neighboring gene STARR-seq mESC enhancer starr_18383 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:28474189-28474376 Neighboring gene STARR-seq mESC enhancer starr_18384 Neighboring gene PHD finger protein 5B, pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10431 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:28516760-28516943 Neighboring gene zinc finger protein 60

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC112415

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001112731.1 → NP_001106202.1  uncharacterized protein LOC112415

    See identical proteins and their annotated locations for NP_001106202.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK141645, BC060708, CF727352
    Consensus CDS
    CCDS21029.1
    UniProtKB/TrEMBL
    G3X9H3
    Related
    ENSMUSP00000112494.2, ENSMUST00000120004.8
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  2. NM_198417.2 → NP_940809.2  uncharacterized protein LOC112415

    See identical proteins and their annotated locations for NP_940809.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' UTR exon, as compared to variant 1.
    Source sequence(s)
    BC060708, BQ770435
    Consensus CDS
    CCDS21029.1
    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    27374086..27405909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030241994.2 → XP_030097854.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  2. XM_030241995.1 → XP_030097855.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  3. XM_030241993.1 → XP_030097853.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  4. XM_036152574.1 → XP_036008467.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Related
    ENSMUSP00000075755.7, ENSMUST00000076421.7
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  5. XM_030241992.2 → XP_030097852.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  6. XM_036152572.1 → XP_036008465.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]

  7. XM_036152573.1 → XP_036008466.1  uncharacterized protein LOC112415 isoform X1

    UniProtKB/TrEMBL
    G3X9H3
    Conserved Domains (4) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:226 → 637
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:537 → 557
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl30559
    Location:174 → 239
    PriA; Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair]
Nucleotide Protein Strain
Heading Accession and Version

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