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ARHGEF1 Rho guanine nucleotide exchange factor 1 [ Bos indicus (zebu cattle) ]

Gene ID: 109572733, updated on 14-Mar-2024

Summary

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Gene symbol
ARHGEF1
Gene description
Rho guanine nucleotide exchange factor 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
34
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 18 NC_032667.1 (51058125..51078673, complement)

Chromosome 18 - NC_032667.1Genomic Context describing neighboring genes Neighboring gene Rab acceptor 1 Neighboring gene ETS repressor factor like Neighboring gene CD79a molecule Neighboring gene ribosomal protein S19

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032667.1 Chromosome 18 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A preliminary sketch of horn cancer transcriptome in Indian zebu cattle. Tripathi AK, et al. Gene, 2012 Feb 1. PMID 22134011

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032667.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    51058125..51078673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019979794.1 → XP_019835353.1  rho guanine nucleotide exchange factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P5DCX5
    Conserved Domains (4) summary
    smart00325
    Location:479 → 662
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd14679
    Location:697 → 821
    PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl26386
    Location:272 → 465
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  2. XM_019979795.1 → XP_019835354.1  rho guanine nucleotide exchange factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P5DCX5
    Conserved Domains (4) summary
    smart00325
    Location:479 → 662
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd14679
    Location:697 → 821
    PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl26386
    Location:272 → 465
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  3. XM_019979796.1 → XP_019835355.1  rho guanine nucleotide exchange factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P5DCX5
    Conserved Domains (4) summary
    smart00325
    Location:479 → 662
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd14679
    Location:697 → 821
    PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl26386
    Location:272 → 465
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  4. XM_019979792.1 → XP_019835351.1  rho guanine nucleotide exchange factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P5DAR6
    Conserved Domains (4) summary
    smart00325
    Location:496 → 679
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd14679
    Location:714 → 838
    PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
    cl02565
    Location:70 → 262
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl26386
    Location:289 → 482
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  5. XM_019979793.1 → XP_019835352.1  rho guanine nucleotide exchange factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P5DE28
    Conserved Domains (4) summary
    smart00325
    Location:492 → 675
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd14679
    Location:710 → 834
    PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
    cl02565
    Location:70 → 262
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl26386
    Location:289 → 478
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  6. XM_019979797.1 → XP_019835356.1  rho guanine nucleotide exchange factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A6P5DAS2
    Conserved Domains (4) summary
    smart00325
    Location:436 → 619
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03169
    Location:302 → 421
    PHA03169; hypothetical protein; Provisional
    cd14679
    Location:654 → 778
    PH_p115RhoGEF; Rho guanine nucleotide exchange factor Pleckstrin homology domain
    cl02565
    Location:70 → 262
    RGS; Regulator of G protein signaling (RGS) domain superfamily
Nucleotide Protein
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