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LOC109279993 VISTA enhancer mm774 [ Mus musculus (house mouse) ]

Gene ID: 109279993, updated on 8-Feb-2024

Summary

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Gene symbol
LOC109279993
Gene description
VISTA enhancer mm774
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mm774; Rr1449
Summary
This locus represents a conserved genomic element that can function as an enhancer. It can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic hindbrain, midbrain and forebrain of transgenic mice. This locus also includes an enhancer that was validated by the STARR-seq (self-transcribing active regulatory region sequencing) reporter assay in ground-state (2iL) mouse embryonic stem cells, where it was defined as a C1 class enhancer that overlaps an active chromatin signature. [provided by RefSeq, Jul 2023]
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Genomic context

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Location:
4; 4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (65155472..65157974)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (65237235..65239737)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10455 Neighboring gene predicted gene, 23950 Neighboring gene STARR-seq mESC enhancer starr_10456 Neighboring gene STARR-seq mESC enhancer starr_10457 Neighboring gene STARR-seq mESC enhancer starr_10458 Neighboring gene predicted gene 11218 Neighboring gene STARR-seq mESC enhancer starr_10459 Neighboring gene STARR-seq mESC enhancer starr_10460 Neighboring gene pregnancy-associated plasma protein A Neighboring gene STARR-seq mESC enhancer starr_10462 Neighboring gene STARR-seq mESC enhancer starr_10463 Neighboring gene astrotactin 2 Neighboring gene STARR-seq mESC enhancer starr_10465 Neighboring gene predicted gene, 31533 Neighboring gene tripartite motif-containing 32

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells. Peng T, et al. Genome Biol, 2020 Sep 10. PMID 32912294, Free PMC Article
  2. VISTA Enhancer Browser--a database of tissue-specific human enhancers. Visel A, et al. Nucleic Acids Res, 2007 Jan. PMID 17130149, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • STARR-seq mESC enhancer starr_10461
  • regulatory region 1449

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054265.1 

    Range
    101..2603
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    65155472..65157974
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version