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ADAM19 ADAM metallopeptidase domain 19 [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102946400, updated on 10-Mar-2024

Summary

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Gene symbol
ADAM19
Gene description
ADAM metallopeptidase domain 19
Locus tag
UY3_05747
See related
EnsemblRapid:ENSCMYG00015017475
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
25
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 8 NC_057854.1 (3173976..3227737)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 8 NC_051248.1 (3175824..3227737)

Chromosome 8 - NC_057854.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122466800 Neighboring gene tRNA-histidine guanylyltransferase 1 like Neighboring gene SRY-box transcription factor 30 Neighboring gene 40S ribosomal protein S25-like Neighboring gene NIPA like domain containing 4 Neighboring gene cytoplasmic FMR1 interacting protein 2 Neighboring gene fibronectin type III domain containing 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 19
Names
Disintegrin and metalloproteinase domain-containing protein 19

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_057854.1 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    3173976..3227737
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043521624.1 → XP_043377559.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X5

    Conserved Domains (5) summary
    smart00050
    Location:357 → 431
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:433 → 578
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:677 → 832
    PHA03378; EBNA-3B; Provisional
    pfam01421
    Location:142 → 340
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:2 → 94
    Pep_M12B_propep; Reprolysin family propeptide

  2. XM_043521625.1 → XP_043377560.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X5

    Conserved Domains (5) summary
    smart00050
    Location:357 → 431
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:433 → 578
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:677 → 832
    PHA03378; EBNA-3B; Provisional
    pfam01421
    Location:142 → 340
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:2 → 94
    Pep_M12B_propep; Reprolysin family propeptide

  3. XM_043521626.1 → XP_043377561.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X6

    UniProtKB/TrEMBL
    M7BY93
    Conserved Domains (5) summary
    smart00050
    Location:325 → 399
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:401 → 546
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:645 → 800
    PHA03378; EBNA-3B; Provisional
    pfam01421
    Location:110 → 308
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:2 → 62
    Pep_M12B_propep; Reprolysin family propeptide

  4. XM_037906645.1 → XP_037762573.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X1

    Related
    ENSCMYP00015026724.1, ENSCMYT00015032833.1
    Conserved Domains (5) summary
    smart00050
    Location:426 → 500
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:502 → 647
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:746 → 901
    PHA03378; EBNA-3B; Provisional
    pfam01421
    Location:211 → 409
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:59 → 163
    Pep_M12B_propep; Reprolysin family propeptide

  5. XM_037906647.1 → XP_037762575.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X3

    Conserved Domains (5) summary
    smart00050
    Location:426 → 500
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:504 → 618
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:717 → 872
    PHA03378; EBNA-3B; Provisional
    pfam01421
    Location:211 → 409
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:59 → 163
    Pep_M12B_propep; Reprolysin family propeptide

  6. XM_037906646.2 → XP_037762574.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X2

    Conserved Domains (5) summary
    smart00050
    Location:426 → 500
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:502 → 647
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:767 → 900
    PHA03378; EBNA-3B; Provisional
    pfam01421
    Location:211 → 409
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:59 → 163
    Pep_M12B_propep; Reprolysin family propeptide

  7. XM_043521623.1 → XP_043377558.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X4

    Conserved Domains (4) summary
    smart00050
    Location:426 → 500
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:504 → 618
    ACR; ADAM Cysteine-Rich Domain
    PHA03378
    Location:738 → 871
    PHA03378; EBNA-3B; Provisional
    cd04269
    Location:211 → 407
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
Nucleotide Protein
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