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APH1A aph-1 homolog A, gamma-secretase subunit [ Myotis davidii ]

Gene ID: 102766022, updated on 30-Mar-2024

Summary

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Gene symbol
APH1A
Gene description
aph-1 homolog A, gamma-secretase subunit
Locus tag
MDA_GLEAN10009651
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis davidii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current ASM32734v1 (GCF_000327345.1) Unplaced Scaffold NW_006285129.1 (260567..276134, complement)

NW_006285129.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing O1 Neighboring gene 14-3-3 protein theta-like Neighboring gene acidic nuclear phosphoprotein 32 family member E Neighboring gene carbonic anhydrase 14 Neighboring gene chromosome unknown C1orf54 homolog Neighboring gene circadian associated repressor of transcription

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006285129.1 Unplaced Scaffold Reference ASM32734v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of gamma-secretase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-secretase subunit APH-1A
Names
APH1A gamma secretase subunit
Gamma-secretase subunit APH-1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis davidii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM32734v1

Genomic

  1. NW_006285129.1 Reference ASM32734v1

    Range
    260567..276134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015558715.1 → XP_015414201.1  gamma-secretase subunit APH-1A isoform X2

    UniProtKB/TrEMBL
    L5MES2
    Conserved Domains (1) summary
    pfam06105
    Location:3 → 233
    Aph-1; Aph-1 protein

  2. XM_006755628.2 → XP_006755691.1  gamma-secretase subunit APH-1A isoform X3

    UniProtKB/TrEMBL
    L5MES2
    Conserved Domains (1) summary
    pfam06105
    Location:3 → 233
    Aph-1; Aph-1 protein

  3. XM_006755627.2 → XP_006755690.1  gamma-secretase subunit APH-1A isoform X1

    UniProtKB/TrEMBL
    L5MES2
    Conserved Domains (1) summary
    pfam06105
    Location:3 → 233
    Aph-1; Aph-1 protein

RNA

  1. XR_001512521.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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