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APH1A aph-1 homolog A, gamma-secretase subunit [ Vicugna pacos (alpaca) ]

Gene ID: 102540611, updated on 10-Mar-2024

Summary

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Gene symbol
APH1A
Gene description
aph-1 homolog A, gamma-secretase subunit
Gene type
protein coding
RefSeq status
MODEL
Organism
Vicugna pacos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
102 current VicPac3.1 (GCF_000164845.3) 21 Unlocalized Scaffold NW_021964201.1 (3898406..3902035, complement)
101 previous assembly Vicugna_pacos-2.0.1 (GCF_000164845.1) Unplaced Scaffold NW_005882975.1 (392310..396087, complement)

NW_021964201.1Genomic Context describing neighboring genes Neighboring gene acidic nuclear phosphoprotein 32 family member E Neighboring gene carbonic anhydrase 14 Neighboring gene chromosome 21 C1orf54 homolog Neighboring gene circadian associated repressor of transcription

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of gamma-secretase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-secretase subunit APH-1A
Names
APH1A gamma secretase subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vicugna pacos Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VicPac3.1 Primary Assembly

Genomic

  1. NW_021964201.1 Reference VicPac3.1 Primary Assembly

    Range
    3898406..3902035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006216931.2 → XP_006216993.1  gamma-secretase subunit APH-1A

    See identical proteins and their annotated locations for XP_006216993.1

    UniProtKB/TrEMBL
    A0A6I9INV9
    Conserved Domains (1) summary
    pfam06105
    Location:3 → 233
    Aph-1; Aph-1 protein
Nucleotide Protein
Heading Accession and Version

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