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ALDH18A1 aldehyde dehydrogenase 18 family member A1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102131075, updated on 3-Apr-2024

Summary

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Gene symbol
ALDH18A1
Gene description
aldehyde dehydrogenase 18 family member A1
See related
Ensembl:ENSMFAG00000001272
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
18
Annotation release Status Assembly Chr Location
102 current MFA1912RKSv2 (GCF_012559485.2) 9 NC_052263.1 (91223867..91273909, complement)
101 previous assembly Macaca_fascicularis_5.0 (GCF_000364345.1) 9 NC_022280.1 (94272512..94322933, complement)

Chromosome 9 - NC_052263.1Genomic Context describing neighboring genes Neighboring gene sorbin and SH3 domain containing 1 Neighboring gene 40S ribosomal protein S3a-like Neighboring gene tectonic family member 3 Neighboring gene ectonucleoside triphosphate diphosphohydrolase 1 Neighboring gene hsc70-interacting protein-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutamate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutamate-5-semialdehyde dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proline biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
delta-1-pyrroline-5-carboxylate synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca fascicularis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MFA1912RKSv2 Primary Assembly

Genomic

  1. NC_052263.1 Reference MFA1912RKSv2 Primary Assembly

    Range
    91223867..91273909 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045361293.1 → XP_045217228.1  delta-1-pyrroline-5-carboxylate synthase isoform X3

    Conserved Domains (1) summary
    TIGR01092
    Location:1 → 683
    P5CS; delta l-pyrroline-5-carboxylate synthetase

  2. XM_005566057.3 → XP_005566114.1  delta-1-pyrroline-5-carboxylate synthase isoform X2

    See identical proteins and their annotated locations for XP_005566114.1

    UniProtKB/TrEMBL
    A0A7N9C918
    Conserved Domains (1) summary
    TIGR01092
    Location:64 → 792
    P5CS; delta l-pyrroline-5-carboxylate synthetase

  3. XM_005566054.3 → XP_005566111.1  delta-1-pyrroline-5-carboxylate synthase isoform X1

    See identical proteins and their annotated locations for XP_005566111.1

    UniProtKB/TrEMBL
    A0A2K5U7W0, A0A7N9C918
    Related
    ENSMFAP00000008394.1
    Conserved Domains (3) summary
    TIGR01092
    Location:64 → 794
    P5CS; delta l-pyrroline-5-carboxylate synthetase
    cd07079
    Location:364 → 766
    ALDH_F18-19_ProA-GPR; Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19
    cd04256
    Location:63 → 354
    AAK_P5CS_ProBA; AAK_P5CS_ProBA: Glutamate-5-kinase (G5K) domain of the bifunctional delta 1-pyrroline-5-carboxylate synthetase (P5CS), composed of an N-terminal G5K (ProB) and a C-terminal glutamyl 5- phosphate reductase (G5PR, ProA), the first and second enzyme ...

  4. XM_045361294.1 → XP_045217229.1  delta-1-pyrroline-5-carboxylate synthase isoform X3

    Conserved Domains (1) summary
    TIGR01092
    Location:1 → 683
    P5CS; delta l-pyrroline-5-carboxylate synthetase

  5. XM_045361292.1 → XP_045217227.1  delta-1-pyrroline-5-carboxylate synthase isoform X2

    Conserved Domains (1) summary
    TIGR01092
    Location:64 → 792
    P5CS; delta l-pyrroline-5-carboxylate synthetase

  6. XM_005566055.3 → XP_005566112.1  delta-1-pyrroline-5-carboxylate synthase isoform X1

    See identical proteins and their annotated locations for XP_005566112.1

    UniProtKB/TrEMBL
    A0A2K5U7W0, A0A7N9C918
    Related
    ENSMFAP00000008424.1
    Conserved Domains (3) summary
    TIGR01092
    Location:64 → 794
    P5CS; delta l-pyrroline-5-carboxylate synthetase
    cd07079
    Location:364 → 766
    ALDH_F18-19_ProA-GPR; Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19
    cd04256
    Location:63 → 354
    AAK_P5CS_ProBA; AAK_P5CS_ProBA: Glutamate-5-kinase (G5K) domain of the bifunctional delta 1-pyrroline-5-carboxylate synthetase (P5CS), composed of an N-terminal G5K (ProB) and a C-terminal glutamyl 5- phosphate reductase (G5PR, ProA), the first and second enzyme ...
Nucleotide Protein
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