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Araf A-Raf proto-oncogene, serine/threonine kinase [ Mesocricetus auratus (golden hamster) ]

Gene ID: 101826679, updated on 8-Mar-2024

Summary

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Gene symbol
Araf
Gene description
A-Raf proto-oncogene, serine/threonine kinase
See related
EnsemblRapid:ENSMAUG00000009999
Gene type
protein coding
RefSeq status
MODEL
Organism
Mesocricetus auratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429213.1 (1764056..1775742, complement)
102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801801.1 (425599..438058, complement)

NW_024429213.1Genomic Context describing neighboring genes Neighboring gene complement factor properdin Neighboring gene synapsin I Neighboring gene TIMP metallopeptidase inhibitor 1 Neighboring gene zinc finger protein 157 Neighboring gene zinc finger protein 157

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. McCann KE, et al. Sci Rep, 2017 Jan 10. PMID 28071753, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase A-Raf
Names
v-raf murine sarcoma 3611 viral oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Maur_2.0 Primary Assembly

Genomic

  1. NW_024429213.1 Reference BCM_Maur_2.0 Primary Assembly

    Range
    1764056..1775742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040733772.1 → XP_040589706.1  serine/threonine-protein kinase A-Raf isoform X1

    UniProtKB/TrEMBL
    A0A3Q0C8S8
    Conserved Domains (3) summary
    smart00109
    Location:99 → 144
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    cd17133
    Location:19 → 91
    RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF
    cl21453
    Location:318 → 582
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040733773.1 → XP_040589707.1  serine/threonine-protein kinase A-Raf isoform X1

    UniProtKB/TrEMBL
    A0A3Q0C8S8
    Conserved Domains (3) summary
    smart00109
    Location:99 → 144
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    cd17133
    Location:19 → 91
    RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF
    cl21453
    Location:318 → 582
    PKc_like; Protein Kinases, catalytic domain

  3. XM_040733776.1 → XP_040589710.1  serine/threonine-protein kinase A-Raf isoform X5

    UniProtKB/TrEMBL
    A0A3Q0C8S8
    Conserved Domains (3) summary
    smart00109
    Location:99 → 144
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    cd17133
    Location:19 → 91
    RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF
    cl21453
    Location:318 → 528
    PKc_like; Protein Kinases, catalytic domain

  4. XM_040733774.1 → XP_040589708.1  serine/threonine-protein kinase A-Raf isoform X3

    UniProtKB/TrEMBL
    A0A3Q0C8S8
    Conserved Domains (3) summary
    smart00109
    Location:99 → 144
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    cd17133
    Location:19 → 91
    RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF
    cl21453
    Location:312 → 576
    PKc_like; Protein Kinases, catalytic domain

  5. XM_021222760.2 → XP_021078419.1  serine/threonine-protein kinase A-Raf isoform X2

    UniProtKB/TrEMBL
    A0A3Q0C8S8, A0A3Q0CE13
    Conserved Domains (3) summary
    cd01816
    Location:20 → 91
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    pfam00130
    Location:99 → 146
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl21453
    Location:313 → 577
    PKc_like; Protein Kinases, catalytic domain

  6. XM_040733775.1 → XP_040589709.1  serine/threonine-protein kinase A-Raf isoform X4

    UniProtKB/TrEMBL
    A0A1U7R4J8, A0A3Q0C8S8
    Related
    ENSMAUP00000008659.2, ENSMAUT00000012491.2
    Conserved Domains (3) summary
    cd17133
    Location:19 → 91
    RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF
    cd20870
    Location:96 → 147
    C1_A_C-Raf; protein kinase C conserved region 1 (C1 domain) found in A- and C-Raf (Rapidly Accelerated Fibrosarcoma) kinases, and similar proteins
    cl21453
    Location:307 → 571
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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