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Aars1 alanyl-tRNA synthetase 1 [ Mesocricetus auratus (golden hamster) ]

Gene ID: 101822663, updated on 8-Mar-2024

Summary

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Gene symbol
Aars1
Gene description
alanyl-tRNA synthetase 1
See related
EnsemblRapid:ENSMAUG00000021342
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mesocricetus auratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
Also known as
Aars; AlaRS
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429183.1 (12856588..12880003, complement)
102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801641.1 (3834246..3857680)

NW_024429183.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110341444 Neighboring gene exosome component 6 Neighboring gene ATP-dependent RNA helicase DDX19B Neighboring gene ATP-dependent RNA helicase DDX19A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A hamster temperature-sensitive alanyl-tRNA synthetase mutant causes degradation of cell-cycle related proteins and apoptosis. Wang Y, et al. J Biochem, 2004 Jan. PMID 14999004
  2. Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters. Ying B, et al. Virology, 2015 Nov. PMID 26319212, Free PMC Article
  3. De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. McCann KE, et al. Sci Rep, 2017 Jan 10. PMID 28071753, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables alanine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in alanyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tRNA modification IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alanine--tRNA ligase, cytoplasmic
Names
alanyl trna synthetase
NP_001268606.1
XP_012971020.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001281677.1 → NP_001268606.1  alanine--tRNA ligase, cytoplasmic

    See identical proteins and their annotated locations for NP_001268606.1

    Status: PROVISIONAL

    Source sequence(s)
    AB097816
    UniProtKB/Swiss-Prot
    Q8CFX8
    UniProtKB/TrEMBL
    A0A1U7Q7W1
    Conserved Domains (6) summary
    PLN02900
    Location:2 → 961
    PLN02900; alanyl-tRNA synthetase
    cd00673
    Location:7 → 254
    AlaRS_core; Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of ...
    pfam02272
    Location:886 → 955
    DHHA1; DHHA1 domain
    cl02787
    Location:495 → 531
    Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins
    cl08469
    Location:525 → 753
    tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain
    cl10459
    Location:402 → 485
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families

RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Maur_2.0 Primary Assembly

Genomic

  1. NW_024429183.1 Reference BCM_Maur_2.0 Primary Assembly

    Range
    12856588..12880003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013115566.3 → XP_012971020.1  alanine--tRNA ligase, cytoplasmic isoform X1

    See identical proteins and their annotated locations for XP_012971020.1

    UniProtKB/Swiss-Prot
    Q8CFX8
    UniProtKB/TrEMBL
    A0A1U7Q7W1
    Related
    ENSMAUP00000024504.2, ENSMAUT00000028522.2
    Conserved Domains (6) summary
    PLN02900
    Location:2 → 961
    PLN02900; alanyl-tRNA synthetase
    cd00673
    Location:7 → 254
    AlaRS_core; Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of ...
    pfam02272
    Location:886 → 955
    DHHA1; DHHA1 domain
    cl02787
    Location:495 → 531
    Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins
    cl08469
    Location:525 → 753
    tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain
    cl10459
    Location:402 → 485
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CFX8.1 GenPept UniProtKB/Swiss-Prot:Q8CFX8

Gene LinkOut

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