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Atf6 activating transcription factor 6 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101706597, updated on 8-Mar-2024

Summary

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Gene symbol
Atf6
Gene description
activating transcription factor 6
See related
Ensembl:ENSHGLG00000019506
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624826.1 (189899..412540)

NW_004624826.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110345849 Neighboring gene Fc receptor like B Neighboring gene dual specificity phosphatase 12 Neighboring gene dnaJ homolog subfamily C member 28-like Neighboring gene DDB1- and CUL4-associated factor 8 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene metal-response element-binding transcription factor 2 pseudogene Neighboring gene olfactomedin like 2B Neighboring gene probable G-protein coupled receptor 160

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624826 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.
    Title: CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of proteasome activator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclic AMP-dependent transcription factor ATF-6 alpha
Names
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624826.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    189899..412540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013065761.2 → XP_012921215.1  cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1

    Conserved Domains (2) summary
    cd14700
    Location:298 → 349
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
    pfam02252
    Location:628 → 769
    PA28_beta; Proteasome activator pa28 beta subunit

  2. XM_021244746.1 → XP_021100405.1  cyclic AMP-dependent transcription factor ATF-6 alpha isoform X2

    Conserved Domains (2) summary
    cd14700
    Location:298 → 349
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
    pfam02252
    Location:624 → 768
    PA28_beta; Proteasome activator pa28 beta subunit

  3. XM_021244747.1 → XP_021100406.1  cyclic AMP-dependent transcription factor ATF-6 alpha isoform X3

    Conserved Domains (2) summary
    cd14700
    Location:298 → 349
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
    pfam02252
    Location:578 → 722
    PA28_beta; Proteasome activator pa28 beta subunit

  4. XM_021244748.1 → XP_021100407.1  cyclic AMP-dependent transcription factor ATF-6 alpha isoform X5

    UniProtKB/TrEMBL
    G5BWG3
    Conserved Domains (2) summary
    cd14700
    Location:298 → 349
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
    cl26365
    Location:147 → 214
    PLN03008; Phospholipase D delta

  5. XM_021244749.1 → XP_021100408.1  cyclic AMP-dependent transcription factor ATF-6 alpha isoform X6

    UniProtKB/TrEMBL
    G5BWG3
    Conserved Domains (2) summary
    cd14700
    Location:298 → 349
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
    cl26365
    Location:147 → 214
    PLN03008; Phospholipase D delta

  6. XM_004865155.2 → XP_004865212.1  cyclic AMP-dependent transcription factor ATF-6 alpha isoform X4

    UniProtKB/TrEMBL
    G5BWG3
    Related
    ENSHGLP00000027428.1, ENSHGLT00000027670.1
    Conserved Domains (1) summary
    cd14700
    Location:298 → 349
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
Nucleotide Protein
Heading Accession and Version

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