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ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 [ Felis catus (domestic cat) ]

Gene ID: 101096009, updated on 8-Mar-2024

Summary

Official Symbol
ADAMTS8
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 8
Primary source
VGNC:VGNC:59597
See related
EnsemblRapid:ENSFCTG00005014052
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
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Genomic context

Location:
chromosome: D1
Exon count:
9
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D1 NC_058377.1 (27070171..27091345, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D1 NC_018732.3 (27177588..27198870, complement)

Chromosome D1 - NC_058377.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 44 Neighboring gene uncharacterized LOC109491894 Neighboring gene 40S ribosomal protein S29-like Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 15 Neighboring gene uncharacterized LOC123380408

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058377.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    27070171..27091345 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019812925.3XP_019668484.3  A disintegrin and metalloproteinase with thrombospondin motifs 8

    UniProtKB/TrEMBL
    A0A337S1I2
    Related
    ENSFCTP00005028335.1, ENSFCTT00005040166.1
    Conserved Domains (4) summary
    smart00209
    Location:682734
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:372579
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:843962
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:601667
    ADAM_CR; ADAM cysteine-rich