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APOBEC3G apolipoprotein B mRNA editing enzyme catalytic subunit 3G [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100982453, updated on 2-May-2024

Summary

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Gene symbol
APOBEC3G
Gene description
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
See related
Ensembl:ENSPPAG00000031519
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human all
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Genomic context

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Location:
chromosome: 23
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 23 NC_085927.1 (48916836..48935652)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 22 NC_073271.1 (51608323..51627146)

Chromosome 23 - NC_085927.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3D Neighboring gene DNA dC->dU-editing enzyme APOBEC-3F Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3H Neighboring gene chromobox 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rapid evolution of primate antiviral enzyme APOBEC3G. Zhang J, et al. Hum Mol Genet, 2004 Aug 15. PMID 15198990
  2. Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. Sawyer SL, et al. PLoS Biol, 2004 Sep. PMID 15269786, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytidine deaminase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA cytosine deamination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytidine to uridine editing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA dC->dU-editing enzyme APOBEC-3G
Names
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_085927.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    48916836..48935652
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034949100.4 → XP_034804991.1  DNA dC->dU-editing enzyme APOBEC-3G isoform X1

    UniProtKB/Swiss-Prot
    Q694B6, Q6DVQ1
    Conserved Domains (2) summary
    pfam18772
    Location:92 → 274
    APOBEC2
    pfam18782
    Location:275 → 459
    NAD2; Novel AID APOBEC clade 2

  2. XM_034949101.4 → XP_034804992.1  DNA dC->dU-editing enzyme APOBEC-3G isoform X2

    UniProtKB/Swiss-Prot
    Q694B6, Q6DVQ1
    Conserved Domains (2) summary
    pfam18772
    Location:12 → 194
    APOBEC2
    pfam18782
    Location:195 → 379
    NAD2; Novel AID APOBEC clade 2

  3. XM_008975103.6 → XP_008973351.2  DNA dC->dU-editing enzyme APOBEC-3G isoform X3

    UniProtKB/Swiss-Prot
    Q694B6, Q6DVQ1
    Conserved Domains (2) summary
    pfam18772
    Location:1 → 127
    APOBEC2
    pfam18782
    Location:128 → 312
    NAD2; Novel AID APOBEC clade 2

  4. XM_055106025.2 → XP_054962000.1  DNA dC->dU-editing enzyme APOBEC-3G isoform X3

  5. XM_055106024.2 → XP_054961999.1  DNA dC->dU-editing enzyme APOBEC-3G isoform X3

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q694B6.1 GenPept UniProtKB/Swiss-Prot:Q694B6

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