ASTL astacin like metalloendopeptidase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ASTLprovided by VGNC
Official Full Name: astacin like metalloendopeptidaseprovided by VGNC
Primary source: VGNC:VGNC:111351
See related: Ensembl:ENSCAFG00845006271
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	17	NC_051821.1 (35365149..35379752)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	17	NC_006599.4 (34363562..34378272)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	17	NC_049238.1 (34769924..34784663)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	17	NC_049277.1 (34494438..34509160)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	17	NC_049758.1 (34562766..34577482)

Chromosome 17 - NC_051821.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: astacin-like metalloendopeptidase

Names: astacin-like metallo-endopeptidase (M12 family)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051821.1 Reference ROS_Cfam_1.0

Range

35365149..35379752

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038690533.1 → XP_038546461.1 astacin-like metalloendopeptidase

UniProtKB/TrEMBL

A0A8C0L2C8, A0A8I3N291, A0A8P0SYT9

Related

ENSCAFP00845008674.1, ENSCAFT00845011117.1

Conserved Domains (2) summary

PHA03247
Location:292 → 445

PHA03247; large tegument protein UL36; Provisional

cl00064
Location:95 → 278

ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049277.1 Alternate UMICH_Zoey_3.1

Range

34494438..34509160

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038499903.1 → XP_038355831.1 astacin-like metalloendopeptidase

Conserved Domains (2) summary

PHA03247
Location:292 → 445

PHA03247; large tegument protein UL36; Provisional

cl00064
Location:95 → 278

ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049758.1 Alternate UNSW_CanFamBas_1.0

Range

34562766..34577482

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038624621.1 → XP_038480549.1 astacin-like metalloendopeptidase

Conserved Domains (2) summary

PHA03247
Location:292 → 445

PHA03247; large tegument protein UL36; Provisional

cl00064
Location:95 → 278

ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049238.1 Alternate UU_Cfam_GSD_1.0

Range

34769924..34784663

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038560593.1 → XP_038416521.1 astacin-like metalloendopeptidase

UniProtKB/TrEMBL

A0A8C0L2C8, A0A8I3N291, A0A8P0SYT9

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

34363562..34378272

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_022404688.2 → XP_022260396.2 astacin-like metalloendopeptidase

UniProtKB/TrEMBL

A0A8C0L2C8, A0A8I3N291, A0A8P0SYT9

Conserved Domains (2) summary

PHA03247
Location:292 → 445

PHA03247; large tegument protein UL36; Provisional

cl00064
Location:95 → 278

ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...