ADRA2B adrenoceptor alpha 2B [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ADRA2Bprovided by VGNC
Official Full Name: adrenoceptor alpha 2Bprovided by VGNC
Primary source: VGNC:VGNC:37675
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: adrab2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	17	NC_051821.1 (35386143..35389429)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	17	NC_006599.4 (34384544..34387878)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	17	NC_049238.1 (34790948..34794282)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	17	NC_049277.1 (34515433..34518767)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	17	NC_049758.1 (34583739..34587073)

Chromosome 17 - NC_051821.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

15STS02 (e-PCR)
- UniSTS:505020

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables alpha2-adrenergic receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in platelet activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of smooth muscle contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: alpha-2B adrenergic receptor; alpha-2B adrenergic receptor

Names: adrenergic, alpha-2B-, receptor; alpha 2B adrenergic receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051821.1 Reference ROS_Cfam_1.0

Range

35386143..35389429

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038690534.1 → XP_038546462.1 LOW QUALITY PROTEIN: alpha-2B adrenergic receptor isoform X1

UniProtKB/TrEMBL

Q2MDQ0

Conserved Domains (2) summary

PTZ00436
Location:200 → 323

PTZ00436; 60S ribosomal protein L19-like protein; Provisional

cd15321
Location:7 → 432

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

NC_049277.1 Alternate UMICH_Zoey_3.1

Range

34515433..34518767

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038499905.1 → XP_038355833.1 alpha-2B adrenergic receptor isoform X2

Conserved Domains (1) summary

cd15321
Location:7 → 205

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_038499904.1 → XP_038355832.1 alpha-2B adrenergic receptor isoform X1

Conserved Domains (1) summary

cd15321
Location:7 → 431

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049758.1 Alternate UNSW_CanFamBas_1.0

Range

34583739..34587073

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038624623.1 → XP_038480551.1 alpha-2B adrenergic receptor isoform X3
XM_038624622.1 → XP_038480550.1 alpha-2B adrenergic receptor isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049238.1 Alternate UU_Cfam_GSD_1.0

Range

34790948..34794282

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038560595.1 → XP_038416523.1 alpha-2B adrenergic receptor isoform X4

UniProtKB/TrEMBL

Q2MDQ0

Conserved Domains (1) summary

cd15321
Location:7 → 205

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_038560594.1 → XP_038416522.1 alpha-2B adrenergic receptor isoform X1

UniProtKB/TrEMBL

A0A8C0RIW0, Q2MDQ0

Conserved Domains (1) summary

cd15321
Location:7 → 431

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

34384544..34387878

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038453132.1 → XP_038309060.1 alpha-2B adrenergic receptor isoform X5

UniProtKB/TrEMBL

Q2MDQ0

Conserved Domains (1) summary

cd15321
Location:7 → 205

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_005642442.4 → XP_005642499.2 alpha-2B adrenergic receptor isoform X1

UniProtKB/TrEMBL

A0A8C0RIW0, Q2MDQ0

Conserved Domains (1) summary

cd15321
Location:7 → 431

7tmA_alpha2B_AR; alpha-2 adrenergic receptors subtype B, member of the class A family of seven-transmembrane G protein-coupled receptors