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ADAM12 ADAM metallopeptidase domain 12 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100599775, updated on 8-Mar-2024

Summary

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Gene symbol
ADAM12
Gene description
ADAM metallopeptidase domain 12
See related
EnsemblRapid:ENSNLEG00000000851
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
24
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 3 NC_044383.1 (7135605..7513093)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 3 NC_019818.1 (7240682..7624142)

Chromosome 3 - NC_044383.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C10orf90 homolog Neighboring gene uncharacterized LOC105739506 Neighboring gene GTP-binding protein SAR1a pseudogene Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 pseudogene Neighboring gene fibronectin type III and ankyrin repeat domains 1 Neighboring gene U2 spliceosomal RNA Neighboring gene DEAH-box helicase 32 (putative)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044383.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    7135605..7513093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030805503.1 → XP_030661363.1  disintegrin and metalloproteinase domain-containing protein 12 isoform X2

    Conserved Domains (5) summary
    smart00050
    Location:436 → 504
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:507 → 649
    ACR; ADAM Cysteine-Rich Domain
    PHA03247
    Location:751 → 902
    PHA03247; large tegument protein UL36; Provisional
    pfam01421
    Location:211 → 413
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:61 → 157
    Pep_M12B_propep; Reprolysin family propeptide

  2. XM_030805511.1 → XP_030661371.1  disintegrin and metalloproteinase domain-containing protein 12 isoform X4

    Conserved Domains (4) summary
    smart00050
    Location:436 → 504
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:507 → 649
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:211 → 413
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:61 → 157
    Pep_M12B_propep; Reprolysin family propeptide

  3. XM_003277782.4 → XP_003277830.1  disintegrin and metalloproteinase domain-containing protein 12 isoform X1

    UniProtKB/TrEMBL
    G1QJE1
    Related
    ENSNLEP00000001035.2, ENSNLET00000001096.3
    Conserved Domains (5) summary
    smart00050
    Location:439 → 507
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:510 → 652
    ACR; ADAM Cysteine-Rich Domain
    PHA03247
    Location:754 → 905
    PHA03247; large tegument protein UL36; Provisional
    pfam01421
    Location:214 → 416
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:61 → 160
    Pep_M12B_propep; Reprolysin family propeptide

  4. XM_030805508.1 → XP_030661368.1  disintegrin and metalloproteinase domain-containing protein 12 isoform X3

    Conserved Domains (4) summary
    smart00050
    Location:439 → 507
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:510 → 652
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:214 → 416
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:61 → 160
    Pep_M12B_propep; Reprolysin family propeptide

  5. XM_030805517.1 → XP_030661377.1  disintegrin and metalloproteinase domain-containing protein 12 isoform X5

    Conserved Domains (4) summary
    smart00050
    Location:436 → 504
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:507 → 649
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:211 → 413
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:61 → 157
    Pep_M12B_propep; Reprolysin family propeptide
Nucleotide Protein
Heading Accession and Version

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