U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ARHGEF1 Rho guanine nucleotide exchange factor 1 [ Sus scrofa (pig) ]

Gene ID: 100518073, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ARHGEF1provided by VGNC
Official Full Name
Rho guanine nucleotide exchange factor 1provided by VGNC
Primary source
VGNC:VGNC:96922
See related
Ensembl:ENSSSCG00000003040
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in spleen (RPKM 34.1), lung (RPKM 24.6) and 8 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 6
Exon count:
33
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (49975957..49995442, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (46030643..46046982)

Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene Rab acceptor 1 Neighboring gene ETS repressor factor like Neighboring gene uncharacterized LOC110260993 Neighboring gene CD79a molecule Neighboring gene ribosomal protein S19

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
rho guanine nucleotide exchange factor 1
Names
Rho guanine nucleotide exchange factor (GEF) 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

    Range
    49975957..49995442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021094443.1 → XP_020950102.1  rho guanine nucleotide exchange factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A287AA62
    Conserved Domains (4) summary
    PHA03418
    Location:537 → 676
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:686 → 870
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:262 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:904 → 1028
    PH-like; Pleckstrin homology-like domain

  2. XM_021094441.1 → XP_020950100.1  rho guanine nucleotide exchange factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A287AA62
    Conserved Domains (4) summary
    PHA03418
    Location:537 → 680
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:690 → 874
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:262 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:908 → 1032
    PH-like; Pleckstrin homology-like domain

  3. XM_021094444.1 → XP_020950103.1  rho guanine nucleotide exchange factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A287AA62, A0A4X1SFI2
    Related
    ENSSSCP00000040702.2, ENSSSCT00000041398.3
    Conserved Domains (4) summary
    PHA03418
    Location:537 → 676
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:686 → 870
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:262 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:904 → 1028
    PH-like; Pleckstrin homology-like domain

  4. XM_021094442.1 → XP_020950101.1  rho guanine nucleotide exchange factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A287AA62, A0A287AJS0, A0A4X1SG16
    Related
    ENSSSCP00000044252.2, ENSSSCT00000045918.3
    Conserved Domains (4) summary
    PHA03418
    Location:537 → 680
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:690 → 874
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:262 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:908 → 1032
    PH-like; Pleckstrin homology-like domain

  5. XM_021094445.1 → XP_020950104.1  rho guanine nucleotide exchange factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A4X1SFL4
    Conserved Domains (4) summary
    smart00325
    Location:630 → 814
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:262 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:848 → 972
    PH-like; Pleckstrin homology-like domain
    cl25865
    Location:512 → 607
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  6. XM_021094446.1 → XP_020950105.1  rho guanine nucleotide exchange factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A4X1SFI8, A0A4X1SFL4
    Related
    ENSSSCP00000042573.2, ENSSSCT00000045905.3
    Conserved Domains (4) summary
    smart00325
    Location:630 → 814
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:262 → 454
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:848 → 972
    PH-like; Pleckstrin homology-like domain
    cl25865
    Location:512 → 607
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  7. XM_021094459.1 → XP_020950118.1  rho guanine nucleotide exchange factor 1 isoform X12

    UniProtKB/TrEMBL
    A0A4X1SG99
    Conserved Domains (4) summary
    smart00325
    Location:421 → 605
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:639 → 763
    PH-like; Pleckstrin homology-like domain
    cl25865
    Location:303 → 398
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  8. XM_021094451.1 → XP_020950110.1  rho guanine nucleotide exchange factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A286ZMZ3, A0A4X1SGQ3, A0A8D0JC99, A0A8D1QH12
    Related
    ENSSSCP00000032827.1, ENSSSCT00000066326.3
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  9. XM_021094447.1 → XP_020950106.1  rho guanine nucleotide exchange factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A480EC91, A0A8D0NR98, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  10. XM_005655907.3 → XP_005655964.2  rho guanine nucleotide exchange factor 1 isoform X11

    UniProtKB/TrEMBL
    A0A4X1SG99
    Related
    ENSSSCP00000053703.2, ENSSSCT00000042668.3
    Conserved Domains (4) summary
    smart00325
    Location:421 → 605
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:639 → 763
    PH-like; Pleckstrin homology-like domain
    cl25865
    Location:303 → 398
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  11. XM_021094455.1 → XP_020950114.1  rho guanine nucleotide exchange factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A286ZMZ3, A0A4X1SGQ3, A0A8D0JC99, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  12. XM_021094450.1 → XP_020950109.1  rho guanine nucleotide exchange factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A480EC91, A0A8D0NR98, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  13. XM_021094456.1 → XP_020950115.1  rho guanine nucleotide exchange factor 1 isoform X9

    UniProtKB/TrEMBL
    A0A8D0NMJ8, A0A8D1U2K8
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 467
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:477 → 661
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:695 → 819
    PH-like; Pleckstrin homology-like domain

  14. XM_021094449.1 → XP_020950108.1  rho guanine nucleotide exchange factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A480EC91, A0A8D0NR98, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  15. XM_021094448.1 → XP_020950107.1  rho guanine nucleotide exchange factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A480EC91, A0A8D0NR98, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  16. XM_021094460.1 → XP_020950119.1  rho guanine nucleotide exchange factor 1 isoform X12

    UniProtKB/TrEMBL
    A0A4X1SG99
    Conserved Domains (4) summary
    smart00325
    Location:421 → 605
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:639 → 763
    PH-like; Pleckstrin homology-like domain
    cl25865
    Location:303 → 398
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  17. XM_021094458.1 → XP_020950117.1  rho guanine nucleotide exchange factor 1 isoform X11

    UniProtKB/TrEMBL
    A0A4X1SG99
    Conserved Domains (4) summary
    smart00325
    Location:421 → 605
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:639 → 763
    PH-like; Pleckstrin homology-like domain
    cl25865
    Location:303 → 398
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  18. XM_021094457.1 → XP_020950116.1  rho guanine nucleotide exchange factor 1 isoform X10

    UniProtKB/TrEMBL
    A0A5G2QAW6, A0A8D0TNE9, A0A8D1U2K8
    Related
    ENSSSCP00000060554.1, ENSSSCT00000076130.2
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 467
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:477 → 661
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:695 → 819
    PH-like; Pleckstrin homology-like domain

  19. XM_021094454.1 → XP_020950113.1  rho guanine nucleotide exchange factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A286ZMZ3, A0A4X1SGQ3, A0A8D0JC99, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

  20. XM_021094452.1 → XP_020950111.1  rho guanine nucleotide exchange factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A286ZMZ3, A0A4X1SGQ3, A0A8D0JC99, A0A8D1QH12
    Conserved Domains (4) summary
    PHA03418
    Location:328 → 471
    PHA03418; hypothetical E4 protein; Provisional
    smart00325
    Location:481 → 665
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cl02565
    Location:53 → 245
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl17171
    Location:699 → 823
    PH-like; Pleckstrin homology-like domain

RNA

  1. XR_002344665.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.