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ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 [ Sus scrofa (pig) ]

Gene ID: 100513765, updated on 8-Mar-2024

Summary

Official Symbol
ADAMTS6provided by VGNC
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 6provided by VGNC
Primary source
VGNC:VGNC:85086
See related
Ensembl:ENSSSCG00000016943
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in heart (RPKM 6.1), lung (RPKM 5.4) and 8 other tissues See more
Orthologs
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Genomic context

Location:
chromosome: 16
Exon count:
24
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 16 NC_010458.4 (43702519..44010820, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 16 NC_010458.3 (46987181..47283577, complement)

Chromosome 16 - NC_010458.4Genomic Context describing neighboring genes Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene uncharacterized LOC110257245 Neighboring gene uncharacterized LOC106506514 Neighboring gene centromere protein K Neighboring gene uncharacterized LOC110257246 Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene tripartite motif containing 23

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010458.4 Reference Sscrofa11.1 Primary Assembly

    Range
    43702519..44010820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021076778.1XP_020932437.1  A disintegrin and metalloproteinase with thrombospondin motifs 6

    UniProtKB/TrEMBL
    A0A4X1UT15, A0A5G2R3K5, A0A8D0NQX9, A0A8D1B5M9, F1SKU0
    Related
    ENSSSCP00000071666.2, ENSSSCT00000089457.2
    Conserved Domains (5) summary
    smart00209
    Location:561613
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:250465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:43191
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:719829
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:10831115
    PLAC; PLAC (protease and lacunin) domain