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adamts6 ADAM metallopeptidase with thrombospondin type 1 motif 6 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100490362, updated on 25-Apr-2024

Summary

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Official Symbol
adamts6provided by Xenbase
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 6provided by Xenbase
Primary source
Xenbase:XB-GENE-951750
See related
Ensembl:ENSXETG00000000457
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (187884629..188045191)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (175092868..175253647)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase domain and WD repeat containing 1 Neighboring gene centromere protein K Neighboring gene CWC27 spliceosome-associated protein Neighboring gene SREK1-interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in extracellular matrix organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    187884629..188045191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002934207.5 → XP_002934253.2  A disintegrin and metalloproteinase with thrombospondin motifs 6

    See identical proteins and their annotated locations for XP_002934253.2

    UniProtKB/TrEMBL
    A0A6I8R5U5, F6YQE5
    Conserved Domains (6) summary
    smart00209
    Location:562 → 614
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:251 → 466
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:43 → 191
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:718 → 830
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1084 → 1116
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:481 → 549
    ADAM_CR_2; ADAM cysteine-rich domain

  2. XM_012967138.3 → XP_012822592.1  A disintegrin and metalloproteinase with thrombospondin motifs 6

    See identical proteins and their annotated locations for XP_012822592.1

    UniProtKB/TrEMBL
    A0A6I8R5U5, F6YQE5
    Related
    ENSXETP00000076547.1, ENSXETT00000073008.2
    Conserved Domains (6) summary
    smart00209
    Location:562 → 614
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:251 → 466
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:43 → 191
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:718 → 830
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1084 → 1116
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:481 → 549
    ADAM_CR_2; ADAM cysteine-rich domain
Nucleotide Protein Strain
Heading Accession and Version

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