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ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 [ Callithrix jacchus (white-tufted-ear marmoset) ]

Gene ID: 100397718, updated on 8-Mar-2024

Summary

Gene symbol
ADAMTS6
Gene description
ADAM metallopeptidase with thrombospondin type 1 motif 6
See related
Ensembl:ENSCJAG00000015704
Gene type
protein coding
RefSeq status
MODEL
Organism
Callithrix jacchus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs
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Genomic context

Location:
chromosome: 2
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 2 NC_071443.1 (140759540..141108818)
105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 2 NC_048384.1 (142350181..142696905)

Chromosome 2 - NC_071443.1Genomic Context describing neighboring genes Neighboring gene tubulin beta-8 chain-like Neighboring gene centromere protein K Neighboring gene 60S ribosomal protein L5-like Neighboring gene actin-related protein 2/3 complex subunit 3 Neighboring gene CWC27 spliceosome associated cyclophilin Neighboring gene THO complex subunit 5 homolog

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

  1. NC_071443.1 Reference mCalJa1.2.pat.X

    Range
    140759540..141108818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035292276.2XP_035148167.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3WPP5, F7B3K4
    Conserved Domains (7) summary
    smart00209
    Location:561613
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:250465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:719829
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43191
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:10831115
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:480548
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:844899
    TSP1_ADAMTS; Thrombospondin type 1 domain
  2. XM_054252627.1XP_054108602.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X2

  3. XM_002744914.4XP_002744960.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3WPP5, F7B3K4
    Related
    ENSCJAP00000029006.1
    Conserved Domains (7) summary
    smart00209
    Location:561613
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:250465
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:719829
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam01562
    Location:43191
    Pep_M12B_propep; Reprolysin family propeptide
    pfam08686
    Location:10831115
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:480548
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:844899
    TSP1_ADAMTS; Thrombospondin type 1 domain
  4. XM_035292277.2XP_035148168.1  A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X3

    Conserved Domains (6) summary
    smart00209
    Location:375427
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:64279
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam05986
    Location:533643
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:897929
    PLAC; PLAC (protease and lacunin) domain
    pfam17771
    Location:294362
    ADAM_CR_2; ADAM cysteine-rich domain
    pfam19030
    Location:658713
    TSP1_ADAMTS; Thrombospondin type 1 domain

RNA

  1. XR_008479849.1 RNA Sequence